2. Gene
  3. HS1BP3 - HCLS1 binding protein 3 Gene

HS1BP3 - HCLS1 binding protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：HCLS1 结合蛋白 3

种属: Homo sapiens

同用名: ETM2; HS1-BP3

基因 ID: 64342 | 基因类型: protein coding

关于 HS1BP3

Cytogenetic location: 2p24.1 Genomic coordinates (GRCh38): 2:20,553,861-20,651,098 (from NCBI)

This gene has 9 transcripts (splice variants) and 145 orthologues. Ubiquitous expression in kidney (RPKM 5.9), adrenal (RPKM 5.4) and 25 other tissues.

功能概要

该基因编码的蛋白质与小鼠 Hs1bp3 具有相似性，Hs1bp3 是一种可能参与淋巴细胞活化的 Hcls1/Hs1 相互作用蛋白。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be involved in lymphocyte activation. [provided by RefSeq, Jul 2008]

HS1BP3 基因产物(1)

mRNA Protein Name
NM_022460.4 NP_071905.3 HCLS1-binding protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
21699750 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21699750 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
21699750 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HS1BP3 蛋白结构

PX

PX: PX domain (34 - 136)

  • 0
  • 100
  • 200
  • 300
  • 392 a.a.
蛋白主名 其他名称

HCLS1-binding protein 3

HS1-binding protein 3

HS1BP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HS1BP3 Q53T59 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
种属内
HS1BP3 Q53T59 FGFR3 Homo sapiens P22607
Y2H Array
32814053
种属内
HS1BP3 Q53T59 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
种属内
HS1BP3 Q53T59 GSN Homo sapiens P06396
Validated Y2H
32814053
种属内
HS1BP3 Q53T59 GSN Homo sapiens P06396
Y2H Pooling
32814053
种属内
HS1BP3 Q53T59 GSN Homo sapiens P06396
Y2H Array
32814053
种属内
HS1BP3 Q53T59 PMP22 Homo sapiens A0A6Q8PF08
Y2H Array
32814053
种属内
HS1BP3 Q53T59 PMP22 Homo sapiens A0A6Q8PF08
Validated Y2H
32814053
种属内
HS1BP3 Q53T59 PMP22 Homo sapiens A0A6Q8PF08
Y2H Pooling
32814053
种属内
HS1BP3 Q53T59 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
种属内
HS1BP3 Q53T59 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
种属内
HS1BP3 Q53T59 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Essential Tremor

Benign Essential Tremor

Familial Tremor

Hereditary Essential Tremor

Essential Hereditary Tremor

Shaky Hand Syndrome

Benign Essential Tremor Syndrome

Tremor Hereditary Essential

Essential Tremor, Susceptibility To

Tremor, Hereditary Essential
Tremor, Hereditary Essential, 1

ETM1

Fet1

Essential Tremor 1

Tremor, Familial Essential, 1

Essential Tremor, Hereditary, 1

Hereditary Essential Tremor 1

Tremor Hereditary Essential, 1

Tremor Familial Essential, 1

Tremor, Hereditary Essential 1

Tremor, Essential Hereditary, Type 1
Myoclonic Cerebellar Dyssynergia

Dyssynergia Cerebellaris Myoclonica

Progressive Cerebellar Tremor

Dentate Cerebellar Ataxia

Dentatorubral Atrophy

Dyssynergia Cerebellaris Progressiva

Myoclonus And Ataxia

Primary Dentatum Atrophy

Progressive Myoclonus Ataxia

Ramsay Hunt Cerebellar Syndrome

Ramsay Hunt Syndrome Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06375 HS1BP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus HS1BP3 VGNC VGNC:62842
Macaca mulatta HS1BP3 VGNC VGNC:82158
Mus musculus HS1BP3 MGD MGI:1913224
Canis familiaris HS1BP3 VGNC VGNC:41790
Bos taurus HS1BP3 VGNC VGNC:59219
Rattus norvegicus HS1BP3 RGD RGD:1311331
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