1. Gene
  2. Icos - inducible T-cell co-stimulator Gene

Icos - inducible T-cell co-stimulator Gene

种属: Rattus norvegicus

同用名: Ailim

基因 ID: 64545 | 基因类型: protein coding

关于 Icos

功能概要

Involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Predicted to be located in external side of plasma membrane. Predicted to be integral component of plasma membrane. Used to study myocarditis. Biomarker of colitis and uveitis. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator). [provided by Alliance of Genome Resources, Apr 2022]

Icos 基因产物(1)

mRNA Protein Name
NM_022610.2 NP_072132.1 inducible T-cell costimulator precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell costimulation IDA
IDA: 通过直接分析推断
11006126 RGD
involved in T cell tolerance induction IMP
IMP: 通过突变表型推断
16220623 RGD
involved in cell-cell adhesion IDA
IDA: 通过直接分析推断
10607749 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

inducible T-cell costimulator

activation-inducible lymphocyte immunomediatory molecule

重组 Icos 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74868 ICOS Protein, Rat (HEK293, Fc) Q9R1T7-1 (E21-L142) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Icos NCBI NCBI:29851
Macaca fascicularis Icos NCBI NCBI:102116512
Mus musculus Icos NCBI NCBI:54167
Macaca mulatta Icos NCBI NCBI:705788