CDCP1 - CUB domain containing protein 1 Gene

中文名称：含 CUB 结构域蛋白 1

种属: Homo sapiens

同用名: CD318; TRASK; SIMA135

基因 ID: 64866 | 基因类型: protein coding

关于 CDCP1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:45,082,277-45,146,482 (from NCBI)

This gene has 3 transcripts (splice variants) and 269 orthologues. Broad expression in esophagus (RPKM 12.2), skin (RPKM 11.1) and 15 other tissues.

功能概要

该基因编码一种跨膜蛋白，该蛋白包含三个细胞外 CUB 结构域，并充当 Src 家族激酶的底物。该蛋白在参与肿瘤侵袭和转移的细胞事件的酪氨酸磷酸化依赖性调节中发挥作用。可变剪接导致该基因的多个转录变体。[RefSeq 提供，2013 年 5 月]

This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

CDCP1 基因产物(2)

mRNA	Protein	Name
NM_022842.5	NP_073753.3	CUB domain-containing protein 1 isoform 1 precursor
NM_178181.3	NP_835488.1	CUB domain-containing protein 1 isoform 2 precursor

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	21233420	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

CUB domain-containing protein 1

membrane glycoprotein gp140

CDCP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CDCP1	Q9H5V8	YES1	Homo sapiens	P07947	Anti Bait CoIP	21233420
种属内	CDCP1	Q9H5V8	SRC	Homo sapiens	P12931	Anti Bait CoIP	21725358
种属内	CDCP1	Q9H5V8	SRC	Homo sapiens	P12931	Anti Bait CoIP	21233420
种属内	CDCP1	Q9H5V8	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	25416956
种属内	CDCP1	Q9H5V8	SDCBP	Homo sapiens	O00560	Validated Y2H	25416956
种属内	CDCP1	Q9H5V8	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	32296183
种属内	CDCP1	Q9H5V8	SDCBP	Homo sapiens	O00560	Y2H Array	25416956
种属内	CDCP1	Q9H5V8	SDCBP	Homo sapiens	O00560	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CDCP1 蛋白

目录号	产品名	蛋白编号	纯度
HY-P70109	CDCP1 Protein, Human (312a.a, HEK293, His)	Q9H5V8-3 (F30-S341)	≥95%
HY-P77891	CDCP1 Protein, Human (HEK293, His)	Q9H5V8-1 (F30-L666)	≥95%
HY-P77892	CDCP1 Protein, Human (HEK293, Fc)	Q9H5V8-1 (F30-L666)	≥95%
HY-P77893	CDCP1 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9H5V8-1 (F30-L666)	≥95%
HY-P700969	CDCP1 Protein, Human (339a.a, HEK293, His)	Q9H5V8-1 (F30-R368)	≥95%

关联疾病

疾病名称

别名

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02318	CDCP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	CDCP1	VGNC	VGNC:39018
Macaca mulatta	CDCP1	VGNC	VGNC:70849
Rattus norvegicus	CDCP1	RGD	RGD:1305578
Felis catus	CDCP1	VGNC	VGNC:60671
Bos taurus	CDCP1	VGNC	VGNC:27089
Mus musculus	CDCP1	MGD	MGI:2442010
Macaca fascicularis	CDCP1	NCBI	NCBI:102129146
Others	CDCP1	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CDCP1 - CUB domain containing protein 1 Gene

关于 CDCP1

功能概要

CDCP1 基因产物(2)

CDCP1 蛋白互作信息

重组 CDCP1 蛋白

关联疾病

直系同源

热门区域

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CDCP1 - CUB domain containing protein 1 Gene

关于 CDCP1

功能概要

CDCP1 基因产物(2)

CDCP1 蛋白互作信息

重组 CDCP1 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z