CDCP1 蛋白, Human (HEK293, His)

CDCP1 protein may be involved in cell adhesion and extracellular matrix association. Phosphorylation of CDCP1 may regulate the balance between anchorage and migration, proliferation, and differentiation. CDCP1 Protein, Human (HEK293, His) is the recombinant human-derived CDCP1 protein, expressed by HEK293 , with C-His labeled tag.

CDCP1 蛋白可能参与细胞粘附以及与细胞外基质的关联。其磷酸化可能在调节锚定和迁移之间的平衡以及增殖和分化方面发挥作用。此外，CDCP1 已显示出作为白血病诊断和鉴定未成熟造血干细胞亚群的新型标记物的前景。它属于四跨膜蛋白网，与肿瘤的进展和转移有关。CDCP1 与多种蛋白质相互作用，包括 CDH2/N-钙粘蛋白、CDH3/P-钙粘蛋白、SDC1/syndecan-1、SDC4/syndecan-4、丝氨酸蛋白酶 ST14/MT-SP1 以及 SRC 和 PRKCG/蛋白激酶 C gamma ，表明它参与各种细胞过程和信号通路。

1.Immobilized Human CDCP1 at 2 μg/mL (100μL/Well). Dose response curve for Anti-CDCP1 Antibody with the EC₅₀ < 8.0 ng/mL determined by ELISA.
2.Measured by its binding ability in a functional ELISA. When Recombinant Human CDCP1 is immobilized at 1 µg/mL (100 µL/well) can bind Human P-Cadherin . The ED₅₀ for this effect is 1.046 μg/mL.

Human

HEK293

C-His

Q9H5V8-1 (F30-L666)

64866  [NCBI]

FEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIEPRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDHRYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSFSYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPYFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQTGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLTPRTVDL

Approximately 90-110 kDa due to the glycosylation.

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5-8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.