Pik3c3 - phosphatidylinositol 3-kinase, catalytic subunit type 3 Gene

中文名称：磷脂酰肌醇 3-激酶，催化亚基 3 型

种属: Rattus norvegicus

关于 Pik3c3

功能概要

该基因编码的蛋白可启动 1-磷脂酰肌醇-3-激酶活性。参与多个过程，包括自噬体组装；磷脂酰肌醇介导的信号；和对亮氨酸的反应。预计位于多种细胞成分中，包括自溶酶体；细胞质囊泡；和中体。预测是磷脂酰肌醇 3-激酶复合物，III 类，I 型和磷脂酰肌醇 3-激酶复合物，III 类，II 型的一部分。预计在几种细胞成分中具有活性，包括核内体；过氧化物酶体；和噬菌体组装位点。与人 PIK3C3（磷脂酰肌醇 3-激酶催化亚基 3 型）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including autophagosome assembly; phosphatidylinositol-mediated signaling; and response to leucine. Predicted to be located in several cellular components, including autolysosome; cytoplasmic vesicle; and midbody. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Predicted to be active in several cellular components, including endosome; peroxisome; and phagophore assembly site. Orthologous to human PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3). [provided by Alliance of Genome Resources, Apr 2022]