2. Gene
  3. CAPRIN2 - caprin family member 2 Gene

CAPRIN2 - caprin family member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：卡普林家族成员 2

种属: Homo sapiens

同用名: EEG1; EEG-1; C1QDC1; RNG140

基因 ID: 65981 | 基因类型: protein coding

关于 CAPRIN2

Cytogenetic location: 12p11.21 Genomic coordinates (GRCh38): 12:30,709,553-30,754,951 (from NCBI)

This gene has 44 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 12.6), brain (RPKM 7.2) and 25 other tissues.

功能概要

该基因编码的蛋白质可以调节 mRNA 的转运。它可能在成红细胞的分化中起作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2016 年 2 月]

The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

CAPRIN2 基因产物(65)

mRNA Protein Name
NM_001002259.3 NP_001002259.1 caprin-2 isoform 1
NM_001206856.3 NP_001193785.1 caprin-2 isoform 4
NM_001319842.2 NP_001306771.1 caprin-2 isoform 5
NM_001319843.2 NP_001306772.1 caprin-2 isoform 6
NM_001319844.2 NP_001306773.1 caprin-2 isoform 7
NM_001319845.2 NP_001306774.1 caprin-2 isoform 8
NM_001319846.2 NP_001306775.1 caprin-2 isoform 8
NM_001385498.1 NP_001372427.1 caprin-2 isoform 9
NM_001385499.1 NP_001372428.1 caprin-2 isoform 10
NM_001385500.1 NP_001372429.1 caprin-2 isoform 11
NM_001385501.1 NP_001372430.1 caprin-2 isoform 8
NM_001385502.1 NP_001372431.1 caprin-2 isoform 12
NM_001385503.1 NP_001372432.1 caprin-2 isoform 12
NM_001385504.1 NP_001372433.1 caprin-2 isoform 13
NM_001385505.1 NP_001372434.1 caprin-2 isoform 13
NM_001385506.1 NP_001372435.1 caprin-2 isoform 13
NM_001385507.1 NP_001372436.1 caprin-2 isoform 7
NM_001385508.1 NP_001372437.1 caprin-2 isoform 14
NM_001385509.1 NP_001372438.1 caprin-2 isoform 14
NM_001385510.1 NP_001372439.1 caprin-2 isoform 15
NM_001385511.1 NP_001372440.1 caprin-2 isoform 16
NM_001385512.1 NP_001372441.1 caprin-2 isoform 16
NM_001385513.1 NP_001372442.1 caprin-2 isoform 16
NM_001385514.1 NP_001372443.1 caprin-2 isoform 17
NM_001385515.1 NP_001372444.1 caprin-2 isoform 17
NM_001385516.1 NP_001372445.1 caprin-2 isoform 39
NM_001385518.1 NP_001372447.1 caprin-2 isoform 18
NM_001385519.1 NP_001372448.1 caprin-2 isoform 19
NM_001385520.1 NP_001372449.1 caprin-2 isoform 19
NM_001385521.1 NP_001372450.1 caprin-2 isoform 20
NM_001385522.1 NP_001372451.1 caprin-2 isoform 20
NM_001385523.1 NP_001372452.1 caprin-2 isoform 21
NM_001385524.1 NP_001372453.1 caprin-2 isoform 21
NM_001385525.1 NP_001372454.1 caprin-2 isoform 21
NM_001385526.1 NP_001372455.1 caprin-2 isoform 22
NM_001385527.1 NP_001372456.1 caprin-2 isoform 23
NM_001385528.1 NP_001372457.1 caprin-2 isoform 24
NM_001385529.1 NP_001372458.1 caprin-2 isoform 24
NM_001385531.1 NP_001372460.1 caprin-2 isoform 5
NM_001385532.1 NP_001372461.1 caprin-2 isoform 5
NM_001385533.1 NP_001372462.1 caprin-2 isoform 5
NM_001385534.1 NP_001372463.1 caprin-2 isoform 5
NM_001385535.1 NP_001372464.1 caprin-2 isoform 25
NM_001385537.1 NP_001372466.1 caprin-2 isoform 26
NM_001385538.1 NP_001372467.1 caprin-2 isoform 27
NM_001385539.1 NP_001372468.1 caprin-2 isoform 28
NM_001385540.1 NP_001372469.1 caprin-2 isoform 29
NM_001385541.1 NP_001372470.1 caprin-2 isoform 29
NM_001385542.1 NP_001372471.1 caprin-2 isoform 30
NM_001385543.1 NP_001372472.1 caprin-2 isoform 31
NM_001385544.1 NP_001372473.1 caprin-2 isoform 32
NM_001385545.1 NP_001372474.1 caprin-2 isoform 33
NM_001385546.1 NP_001372475.1 caprin-2 isoform 34
NM_001385547.1 NP_001372476.1 caprin-2 isoform 35
NM_001385548.1 NP_001372477.1 caprin-2 isoform 35
NM_001385549.1 NP_001372478.1 caprin-2 isoform 35
NM_001385550.1 NP_001372479.1 caprin-2 isoform 36
NM_001385551.1 NP_001372480.1 caprin-2 isoform 36
NM_001385552.1 NP_001372481.1 caprin-2 isoform 36
NM_001385553.1 NP_001372482.1 caprin-2 isoform 37
NM_001385554.1 NP_001372483.1 caprin-2 isoform 36
NM_001385557.1 NP_001372486.1 caprin-2 isoform 38
NM_001385559.1 NP_001372488.1 caprin-2 isoform 26
NM_023925.5 NP_076414.2 caprin-2 isoform 2
NM_032156.5 NP_115532.3 caprin-2 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18762581 GOA
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
18762581 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cell growth IDA
IDA: 通过直接分析推断
14593112 GOA
involved in positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
18762581 GOA
involved in positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
32691935 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18762581 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14593112 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
14593112 GOA
part of receptor complex IDA
IDA: 通过直接分析推断
18762581 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CAPRIN2 蛋白结构

Caprin-1_C

Caprin-1_C: Cytoplasmic activation/proliferation-associated protein-1 C term (687 - 882)

C1q

C1q: C1q domain (949 - 1074)

  • 0
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  • 1000
  • 1077 a.a.
蛋白主名 其他名称

caprin-2

C1q domain-containing protein 1

CAPRIN2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CAPRIN2 Q6IMN6 LRP5 Homo sapiens O75197
Pull Down
18762581
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency 32

COXPD32
Mixed Fibrolamellar Hepatocellular Carcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01898 CAPRIN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-165042 1,2-Dipalmitoyl-3-decanoyl-rac-glycerol / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CAPRIN2 RGD RGD:1593683
Bos taurus CAPRIN2 VGNC VGNC:26752
Macaca mulatta CAPRIN2 VGNC VGNC:70599
Felis catus CAPRIN2 VGNC VGNC:60359
Mus musculus CAPRIN2 MGD MGI:2448541
Canis familiaris CAPRIN2 VGNC VGNC:38709
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