2. Gene
  3. Nde1 - nudE neurodevelopment protein 1 Gene

Nde1 - nudE neurodevelopment protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nude; mNudE; 2810027M15Rik

基因 ID: 67203 | 基因类型: protein coding

关于 Nde1

功能概要

Enables identical protein binding activity and microtubule binding activity. Involved in centrosome duplication and neuron migration. Acts upstream of or within microtubule nucleation; nervous system development; and vesicle transport along microtubule. Located in spindle pole centrosome and synapse. Is expressed in several structures, including body cavity or lining; brain; early conceptus; integumental system; and vertebral axis musculature. Human ortholog(s) of this gene implicated in lissencephaly 4. Orthologous to human NDE1 (nudE neurodevelopment protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Nde1 基因产物(4)

mRNA Protein Name
NM_001114085.1 NP_001107557.1 nuclear distribution protein nudE homolog 1 isoform b
NM_001285503.1 NP_001272432.1 nuclear distribution protein nudE homolog 1 isoform c
NM_001285504.1 NP_001272433.1 nuclear distribution protein nudE homolog 1 isoform d
NM_023317.2 NP_075806.2 nuclear distribution protein nudE homolog 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15571978 MGI
enables microtubule binding IMP
IMP: 通过突变表型推断
15473967 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11163258 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in centrosome duplication IMP
IMP: 通过突变表型推断
15473967 MGI
acts upstream of or within cerebral cortex development IGI
IGI: 通过遗传相互作用推断
18469343 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
15473967 MGI
acts upstream of or within microtubule nucleation IDA
IDA: 通过直接分析推断
11163258 MGI
involved in microtubule organizing center organization IMP
IMP: 通过突变表型推断
11163258 MGI
acts upstream of or within neuroblast proliferation IMP
IMP: 通过突变表型推断
15473967 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
11163258 MGI
acts upstream of or within vesicle transport along microtubule IGI
IGI: 通过遗传相互作用推断
16107726 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
11163258 MGI
located in microtubule organizing center IDA
IDA: 通过直接分析推断
11163258 MGI
located in spindle IDA
IDA: 通过直接分析推断
15473967 MGI
located in spindle pole centrosome IDA
IDA: 通过直接分析推断
15473967 MGI
located in synapse IDA
IDA: 通过直接分析推断
18983980 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear distribution protein nudE homolog 1

nuclear distribution gene E homolog 1

Nde1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Nde1 Q9CZA6 Cenpf Mus musculus Q155P7
Y2H
15939891
种属内
Nde1 Q9CZA6 Cenpf Mus musculus Q155P7
Y2H
11163258
种属间
Nde1 Q9CZA6 DYNC1I1 Homo sapiens O14576
Anti Bait CoIP
19927128
种属间
Nde1 Q9CZA6 PAFAH1B1 Homo sapiens P43034
Y2H
11163258
种属间
Nde1 Q9CZA6 PAFAH1B1 Homo sapiens P43034
Anti Tag CoIP
11163258
种属间
Nde1 Q9CZA6 PAFAH1B1 Homo sapiens P43034
TAP
20360068
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09106 NDE1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nde1 NCBI NCBI:54820
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