2. Gene
  3. Tnfsf13 - tumor necrosis factor (ligand) superfamily, member 13 Gene

Tnfsf13 - tumor necrosis factor (ligand) superfamily, member 13 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: April; Tall2; Trdl1; Tnlg7b; 2310026N09Rik

基因 ID: 69583 | 基因类型: protein coding

关于 Tnfsf13

功能概要

Predicted to enable receptor ligand activity. Acts upstream of or within immunoglobulin mediated immune response; positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and positive regulation of cell population proliferation. Located in external side of plasma membrane. Is expressed in central nervous system; renal vasculature; retina outer nuclear layer; and superior cervical ganglion. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human TNFSF13 (TNF Superfamily member 13). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf13 基因产物(2)

mRNA Protein Name
NM_001159505.1 NP_001152977.1 tumor necrosis factor ligand superfamily member 13 isoform 2
NM_023517.2 NP_076006.2 tumor necrosis factor ligand superfamily member 13 isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of germinal center formation IMP
IMP: 通过突变表型推断
14988498 MGI
acts upstream of or within immunoglobulin mediated immune response IMP
IMP: 通过突变表型推断
14988498 MGI
acts upstream of or within immunoglobulin production in mucosal tissue IMP
IMP: 通过突变表型推断
14988498 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
10973284 MGI
acts upstream of or within positive regulation of germinal center formation IMP
IMP: 通过突变表型推断
14988498 MGI
acts upstream of or within positive regulation of isotype switching to IgA isotypes IMP
IMP: 通过突变表型推断
14988498 MGI
acts upstream of or within regulation of immune response IMP
IMP: 通过突变表型推断
14988498 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
14729948 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor ligand superfamily member 13

a proliferation-inducing ligand

tumor necrosis factor ligand 7b

重组 Tnfsf13 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7320 APRIL/TNFSF13 Protein, Mouse Q9D777 (R50-L241) ≥95%
HY-P7538 APRIL/TNFSF13 Protein, Mouse (HEK293, Fc) Q9D777 (A96-K240) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990070 Zigakibart Inhibitor 98.37% Phase 3
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14823 TNFSF13 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14824 TNFSF13B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfsf13 NCBI NCBI:8741
Canis familiaris Tnfsf13 NCBI NCBI:100568281
Macaca fascicularis Tnfsf13 NCBI
Macaca mulatta Tnfsf13 NCBI NCBI:100551507
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