1. Gene
  2. Sik3 - SIK family kinase 3 Gene

Sik3 - SIK family kinase 3 Gene

中文名称:S IK 家族激酶 3

种属: Mus musculus

同用名: Qsk; SIK-3; mKIAA0999; 5730525O22Rik; 9030204A07Rik

基因 ID: 70661 | 基因类型: protein coding

关于 Sik3

Chromosome 9: 45,924,118-46,135,492 forward strand.GRCm39:CM001002.3

This gene has 7 transcripts (splice variants), 224 orthologues, 19 paralogues and is associated with 223 phenotypes. Ubiquitous expression in cerebellum adult (RPKM 12.2), adrenal adult (RPKM 1.1) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动;镁离子结合活性;和蛋白激酶活性。作用于软骨内骨形态发生的上游或内部;肢体形态发生;和蛋白质定位的调节。位于细胞质中。在 Meckel 的软骨和触须中表达。与人类 SIK3(SIK 家族激酶 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ATP binding activity; magnesium ion binding activity; and protein kinase activity. Acts upstream of or within endochondral bone morphogenesis; limb morphogenesis; and regulation of protein localization. Located in cytoplasm. Is expressed in Meckel's cartilage and vibrissa. Orthologous to human SIK3 (SIK family kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Sik3 基因产物(1)

mRNA Protein Name
NM_027498.3 NP_081774.3 serine/threonine-protein kinase SIK3

Sik3 蛋白结构

STKc_SIK

STKc_SIK: cd14071 (64 - 316)

UBA_SIK3

UBA_SIK3: cd14410 (345 - 389)

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  • 1369 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase SIK3

salt-inducible kinase 3

serine/threonine-protein kinase QSK

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sik3 NCBI NCBI:23387