1. Gene
  2. Vps11 - VPS11, CORVET/HOPS core subunit Gene

Vps11 - VPS11, CORVET/HOPS core subunit Gene

种属: Mus musculus

同用名: 1200011A11Rik

基因 ID: 71732 | 基因类型: protein coding

关于 Vps11

功能概要

Predicted to enable several functions, including protein-macromolecule adaptor activity; syntaxin binding activity; and ubiquitin protein Ligase activity. Acts upstream of or within toxin transport. Located in actin filament; early endosome; and presynaptic active zone. Part of AP-3 adaptor complex and CORVET complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 12. Orthologous to human VPS11 (VPS11 core subunit of CORVET and HOPS complexes). [provided by Alliance of Genome Resources, Apr 2022]

Vps11 基因产物(2)

mRNA Protein Name
NM_001357393.1 NP_001344322.1 vacuolar protein sorting-associated protein 11 homolog isoform 2
NM_027889.2 NP_082165.1 vacuolar protein sorting-associated protein 11 homolog isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14668490 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AP-3 adaptor complex IDA
IDA: 通过直接分析推断
21411634 MGI
part of CORVET complex IDA
IDA: 通过直接分析推断
25266290 MGI
located in actin filament IDA
IDA: 通过直接分析推断
14668490 MGI
located in early endosome IDA
IDA: 通过直接分析推断
14668490 MGI
is active in presynaptic active zone IDA
IDA: 通过直接分析推断
17027648 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vacuolar protein sorting-associated protein 11 homolog

vacuolar protein sorting 11

Vps11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross Vps11 Q91W86 VIPAS39 Homo sapiens Q9H9C1
Anti Bait CoIP
19109425
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vps11 NCBI NCBI:55823