TSPY1 - testis specific protein Y-linked 1 Gene

中文名称：睾丸特异性蛋白 Y 连锁 1

种属: Homo sapiens

同用名: CT78; TSPY; DYS14; pJA923

基因 ID: 7258 | 基因类型: protein coding

关于 TSPY1

Cytogenetic location: Yp11.2 Genomic coordinates (GRCh38): Y:9,466,955-9,469,749 (from NCBI)

This gene has 2 transcripts (splice variants), 198 orthologues, 18 paralogues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 33.8).

功能概要

由该基因编码的蛋白质仅存在于睾丸组织中，可能与精子发生有关。该基因的许多功能性旁系同源基因和假基因在人类中呈簇状存在，但在小鼠中仅发现一个非功能性直系同源基因。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 3 月]

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of this gene are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

TSPY1 基因产物(3)

mRNA	Protein	Name
NM_001197242.2	NP_001184171.1	testis-specific Y-encoded protein 1 isoform TSPY-L
NM_001320964.2	NP_001307893.1	testis-specific Y-encoded protein 1 isoform 3
NM_003308.4	NP_003299.2	testis-specific Y-encoded protein 1 isoform TSPY-S

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	18649364	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TSPY1 蛋白结构

NAP

0
100
200
308 a.a.

蛋白主名

其他名称

testis-specific Y-encoded protein 1

cancer/testis antigen 78

TSPY1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属间	TSPY1	Q01534	Eef1a1	Mus musculus	P10126	Confocal	18649364
种属间	TSPY1	Q01534	Eef1a1	Mus musculus	P10126	Anti Tag CoIP	18649364
种属间	TSPY1	Q01534	Eef1a1	Mus musculus	P10126	Pull Down	18649364
种属间	TSPY1	Q01534	Eef1a1	Mus musculus	P10126	Y2H	18649364

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Gonadoblastoma

GBY

Testicular Seminoma

Seminoma Of Testis	Seminomatous Germ Cell Tumor Of Testis
Testicular Seminomatous Germ Cell Tumor	Seminoma

Partial Deletion Of Y

Partial Chromosome Y Deletion	Partial Deletion Of Y Chromosome Short Arm
Partial Deletion Of Chromosome Y	Partial Deletion Of The Long Arm Of The Y Chromosome
Y-Chromosome Microdeletions	Male Sterility Due To Chromosome Y Deletion
Y Chromosome Deletions

Sudden Infant Death With Dysgenesis Of The Testes Syndrome

SIDDT	Sudden Infant Death-Dysgenesis Of The Testes Syndrome
Sudden Infant Death - Dysgenesis Of The Testes

Turner Syndrome

Monosomy X	Gonadal Dysgenesis Turner Type
Ullrich-Turner Syndrome	Bonnevie-Ullrich Syndrome
Karyotype 45, X	Genital Dwarfism, Turner Type
Gonadal Dysgenesis	45,X
Turner'S Syndrome	Gonadal Dysgenesis - Turner
Monosomy X Syndrome	Xo Syndrome
Genital Dwarfism	45, X Syndrome
Bonnevie-Ulrich Syndrome	Chromosome X Monosomy X
Schereshevkii Turner Syndrome	Turner Varny Syndrome
Ts	45,X Syndrome
45,X/46,Xx Syndrome	Turners Syndrome
Gonadal Dysgenesis, 45,X	X0 Syndrome

Seminoma

Seminoma, Pure

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Testicular Cancer

Testis Cancer	Testicular Carcinoma
Testicular Neoplasms	Malignant Neoplasm Of Testis
Childhood Neoplasm Of The Testis	Neoplasm Of Testis
Pediatric Testicular Neoplasm	Testicular Tumor
Testis Neoplasm	Testicular Tumors
Testicular Neoplasm	Testicular Malignant Germ Cell Tumor
Childhood Testicular Neoplasm	Carcinoma Of The Testis
Cancer Of Testis	Malignant Neoplasm Of Testis, Nos
Malignant Neoplasm Of Testis, Unspecified	Malignant Tumour Of Testis
Testicle Cancer	Primary Malignant Neoplasm Of Testis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15180	TSPY1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	TSPY1	RGD	RGD:3912

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TSPY1 - testis specific protein Y-linked 1 Gene

关于 TSPY1

功能概要

TSPY1 基因产物(3)

TSPY1 蛋白结构

TSPY1 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

TSPY1 - testis specific protein Y-linked 1 Gene

关于 TSPY1

功能概要

TSPY1 基因产物(3)

TSPY1 蛋白结构

TSPY1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z