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  2. USF2 - upstream transcription factor 2, c-fos interacting Gene

USF2 - upstream transcription factor 2, c-fos interacting Gene

中文名称:上游转录因子 2,c-fos 相互作用

种属: Homo sapiens

同用名: FIP; bHLHb12

基因 ID: 7392 | 基因类型: protein coding

关于 USF2

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,268,962-35,279,821 (from NCBI)

This gene has 16 transcripts (splice variants), 247 orthologues and 3 paralogues. Ubiquitous expression in fat (RPKM 22.6), spleen (RPKM 20.0) and 25 other tissues.

功能概要

该基因编码基本螺旋-环-螺旋亮氨酸拉链转录因子家族的成员。编码的蛋白质可以通过富含嘧啶的引发剂 (Inr) 元件和 E-box 基序激活转录,并参与调节多个细胞过程。[RefSeq 提供,2016 年 3 月]

This gene encodes a member of the basic helix-loop-helix leucine zipper family of transcription factors. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes. [provided by RefSeq, Mar 2016]

USF2 基因产物(3)

mRNA Protein Name
NM_001321150.2 NP_001308079.1 upstream stimulatory factor 2 isoform 3
NM_003367.4 NP_003358.1 upstream stimulatory factor 2 isoform 1
NM_207291.3 NP_997174.1 upstream stimulatory factor 2 isoform 2

USF2 蛋白结构

HLH

HLH: Helix-loop-helix DNA-binding domain (236 - 290)

  • 0
  • 100
  • 200
  • 300
  • 346 a.a.
蛋白主名 其他名称

upstream stimulatory factor 2

c-fos interacting protein

USF2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
USF2 Q15853 FOS Homo sapiens Q6FG41 25416956
种属内
USF2 Q15853 TEAD2 Homo sapiens Q15562 25416956
种属内
USF2 Q15853 TEAD2 Homo sapiens Q15562 25416956
种属内
USF2 Q15853 LZTS2 Homo sapiens Q9BRK4 25416956
种属内
USF2 Q15853 LZTS2 Homo sapiens Q9BRK4 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cowden Syndrome

Cowden Disease

Multiple Hamartoma Syndrome

Cowden'S Disease

Lhermitte-Duclos Disease

Cd

Cs

Mham

Dysplastic Gangliocytoma Of Cerebellum

Cowden'S Syndrome

Hamartoma Syndrome, Multiple

Spinocerebellar Ataxia 23

Spinocerebellar Ataxia Type 23

SCA23

Ataxia, Spinocerebellar, Type 23

Microphthalmia

Microphthalmos

Isolated Anophthalmia-Microphthalmia Syndrome

Isolated Microphthalmia-Anophthalmia-Coloboma

Simple Microphthalmos

Clinical Anophthalmia

Isolated Anophthalmia - Microphthalmia

Isolated Pure Microphthalmia

Mac Spectrum

Microphthalmia-Anophthalmia-Coloboma Spectrum

Primitive Anophthalmia

Globe Of Eye Small

Small Eyeball

Hypoplasia Of Eye

Isolated Nanophthalmos

Rudimentary Eye

Dysplasia Of Eye

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Hyperlipidemia, Familial Combined, 3

Familial Combined Hyperlipidemia

Combined Hyperlipidemia, Familial

Mixed Hyperlipidaemia

FCHL3

Hyperlipidemia, Familial Combined

Familial Multiple Lipoprotein-Type Hyperlipidemia

Hyperbetalipoproteinemia With Prebetalipoproteinemia

Type Iib Hyperlipoproteinemia

Hyperlipidemia Familial Combined

Hyperlipoproteinemia Type Iib

Mixed Hyperlipemia

Hyperlipidaemia, Group C

Familial Hypercholesterolaemia With Hyperlipaemia

Familial Hyperbetalipoproteinaemia And Hyperprebetalipoproteinaemia

Hyperbetalipoproteinaemia With Prebetalipoproteinaemia

Hypercholesterolaemia With Endogenous Hyperglyceridaemia

Prebetalipoproteinemia Hyperbetalipoproteinaemia

Remnant Hyperlipoproteinemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus USF2 RGD RGD:620975
Canis familiaris USF2 VGNC VGNC:53999
Mus musculus USF2 MGD MGI:99961