1. Gene
  2. Car12 - carbonic anhydrase 12 Gene

Car12 - carbonic anhydrase 12 Gene

中文名称:碳酸酐酶 12

种属: Mus musculus

同用名: Ca12; CA-XII; 2310047E01Rik

基因 ID: 76459 | 基因类型: protein coding

关于 Car12

Chromosome 9: 66,620,968-66,674,127 forward strand.GRCm39:CM001002.3

This gene has 6 transcripts (splice variants), 215 orthologues, 15 paralogues and is associated with 1 phenotype. Biased expression in kidney adult (RPKM 57.2), limb E14.5 (RPKM 7.3) and 5 other tissues.

功能概要

该基因编码 α 碳酸酐酶家族的膜结合成员,该家族酶催化二氧化碳可逆水合生成碳酸氢盐。这些蛋白质参与多种生物过程,包括呼吸、钙化、酸碱平衡、骨吸收以及房水、脑脊液、唾液和胃酸的形成。可变剪接导致多个转录本变体。 [RefSeq 提供,2015 年 4 月]

This gene encodes a membrane-bound member of the alpha Carbonic Anhydrase family of Enzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. These proteins participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Car12 基因产物(2)

mRNA Protein Name
NM_178396.5 NP_848483.3 carbonic anhydrase 12 isoform 1 precursor
NM_001306148.1 NP_001293077.1 carbonic anhydrase 12 isoform 2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbonate dehydratase activity IDA
IDA: 通过直接分析推断
14660577 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Car12 蛋白结构

alpha_CA

alpha_CA: cl00012 (38 - 289)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
蛋白主名 其他名称

carbonic anhydrase 12

CA XII

carbonate dehydratase XII

carbonic anhydrase XII

重组 Car12 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7716 Carbonic Anhydrase 12 Protein, Mouse (HEK293, His) Q8CI85 (A25-S301) ≥95%