TRIM26 - tripartite motif containing 26 Gene

中文名称：含三方基序 26

种属: Homo sapiens

同用名: AFP; RNF95; ZNF173

关于 TRIM26

功能概要

由该基因编码的蛋白质是三联基序 (TRIM) 家族的成员。 TRIM 基序包括三个锌结合域、一个 RING、一个 B-box 类型 1 和一个 B-box 类型 2，以及一个卷曲螺旋区域。该蛋白质定位于细胞质体。尽管蛋白质的功能未知，但 RING 结构域表明该蛋白质可能具有 DNA 结合活性。该基因定位于 6 号染色体上的主要组织相容性复合体 (MHC) I 类区域。已发现该基因编码相同蛋白质的可变剪接转录变体。[RefSeq 提供，2011 年 6 月]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]