2. Gene
  3. CACNB3 - calcium voltage-gated channel auxiliary subunit beta 3 Gene

CACNB3 - calcium voltage-gated channel auxiliary subunit beta 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：钙电压门控通道辅助亚基 β 3

种属: Homo sapiens

同用名: CAB3; CACNLB3

基因 ID: 784 | 基因类型: protein coding

关于 CACNB3

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:48,814,480-48,828,941 (from NCBI)

This gene has 24 transcripts (splice variants), 280 orthologues and 3 paralogues. Ubiquitous expression in endometrium (RPKM 10.3), ovary (RPKM 7.3) and 21 other tissues.

功能概要

该基因编码电压依赖性钙通道的调节性 β 亚基。 β 亚基由五个结构域组成，它们有助于钙通道表面表达和门控的调节，也可能在转录因子和钙转运的调节中发挥作用。[RefSeq 提供，2011 年 10 月]

This gene encodes a regulatory beta subunit of the voltage-dependent Calcium Channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011]

CACNB3 基因产物(4)

mRNA Protein Name
NM_000725.4 NP_000716.2 voltage-dependent L-type calcium channel subunit beta-3 isoform 1
NM_001206915.2 NP_001193844.1 voltage-dependent L-type calcium channel subunit beta-3 isoform 2
NM_001206916.2 NP_001193845.1 voltage-dependent L-type calcium channel subunit beta-3 isoform 3
NM_001206917.2 NP_001193846.1 voltage-dependent L-type calcium channel subunit beta-3 isoform 4

CACNB3 蛋白结构

VGCC_beta4Aa_N

VGCC_beta4Aa_N: Voltage gated calcium channel subunit beta domain 4Aa N terminal (16 - 58)

Guanylate_kin

Guanylate_kin: Guanylate kinase (176 - 354)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 484 a.a.
蛋白主名 其他名称

voltage-dependent L-type calcium channel subunit beta-3

calcium channel, voltage-dependent, beta 3 subunit

CACNB3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CACNB3 P54284 CTBP2 Homo sapiens P56545-3
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 CTBP2 Homo sapiens P56545-3
Validated Y2H
32296183
种属内
CACNB3 P54284 CTBP2 Homo sapiens P56545-3
Y2H Array
32296183
种属内
CACNB3 P54284 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
种属内
CACNB3 P54284 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
种属内
CACNB3 P54284 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 CIMIP1 Homo sapiens Q9H1P6
Validated Y2H
32296183
种属内
CACNB3 P54284 CIMIP1 Homo sapiens Q9H1P6
Y2H Array
32296183
种属内
CACNB3 P54284 CIMIP1 Homo sapiens Q9H1P6
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 MEOX1 Homo sapiens P50221
Y2H Array
32296183
种属内
CACNB3 P54284 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 SKIC2 Homo sapiens Q15477
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 SKIC2 Homo sapiens Q15477
Validated Y2H
32296183
种属内
CACNB3 P54284 SKIC2 Homo sapiens Q15477
Y2H Array
32296183
种属内
CACNB3 P54284 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 CEP76 Homo sapiens Q8TAP6
Validated Y2H
32296183
种属内
CACNB3 P54284 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
种属内
CACNB3 P54284 GEM Homo sapiens P55040
Validated Y2H
32296183
种属内
CACNB3 P54284 CIAPIN1 Homo sapiens Q6FI81
Y2H Prey Pooling
32296183
种属内
CACNB3 P54284 CIAPIN1 Homo sapiens Q6FI81
Y2H Array
32296183
种属内
CACNB3 P54284 CIAPIN1 Homo sapiens Q6FI81
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Arrhythmogenic Right Ventricular Cardiomyopathy

Arrhythmogenic Right Ventricular Dysplasia

Arvc

Arvd

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

Arvc Cardiomyopathy

Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia

Arvd/C

Right Ventricular Dysplasia, Arrhythmogenic

Ventricular Dysplasia, Right, Arrhythmogenic

Cardiomyopathy, Ventricular, Right, Arrhythmogenic

Dysplasia, Arrhythmogenic Right Ventricular
Distal Hereditary Motor Neuronopathy Type 2

Distal Hereditary Motor Neuropathy, Type Ii

Distal Hereditary Motor Neuropathy Type 2

Distal Hereditary Motor Neuropathy Type Ii

Hmn Ii

Hmn2

Distal Hereditary Motor Neuronopathy, Type Ii

Distal Spinal Muscular Atrophy Type 2

Dhmn2

Dsma2

Neuropathy, Motor, Distal, Hereditary, Type Ii

Spinal Muscular Atrophy, Jerash Type
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01807 CACNB3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CACNB3 RGD RGD:2248
Felis catus CACNB3 VGNC VGNC:60308
Canis familiaris CACNB3 VGNC VGNC:38646
Bos taurus CACNB3 VGNC VGNC:26685
Mus musculus CACNB3 MGD MGI:103307
Macaca mulatta CACNB3 VGNC VGNC:70511
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