PHF23 - PHD finger protein 23 Gene

中文名称：PHD 指蛋白 23

种属: Homo sapiens

同用名: hJUNE-1b

基因 ID: 79142 | 基因类型: protein coding

关于 PHF23

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,235,038-7,240,828 (from NCBI)

This gene has 13 transcripts (splice variants), 212 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 12.0), testis (RPKM 11.9) and 25 other tissues.

功能概要

预测可启用金属离子结合活性。参与自噬体组装的负调控；自噬体成熟的负调控；和蛋白质泛素化的正调控。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable metal ion binding activity. Involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PHF23 基因产物(3)

mRNA	Protein	Name
NM_001284517.2	NP_001271446.1	PHD finger protein 23 isoform 2
NM_001284518.2	NP_001271447.1	PHD finger protein 23 isoform 3
NM_024297.3	NP_077273.2	PHD finger protein 23 isoform 1

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25484098	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of autophagosome assembly	IMP IMP: 通过突变表型推断	25484098	GOA
involved in negative regulation of autophagosome maturation	IMP IMP: 通过突变表型推断	25484098	GOA
involved in positive regulation of protein ubiquitination	IMP IMP: 通过突变表型推断	25484098	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PHF23 蛋白结构

PHD

0
100
200
300
403 a.a.

蛋白主名

其他名称

PHD finger protein 23

PDH-containing protein JUNE-1

PHF23 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	PHF23	Q9BUL5	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	PHF23	Q9BUL5	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	PHF23	Q9BUL5	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	PHF23	Q9BUL5	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
Intra	PHF23	Q9BUL5	HRAS	Homo sapiens	P01112	Y2H Array	32814053
Intra	PHF23	Q9BUL5	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
Intra	PHF23	Q9BUL5	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	PHF23	Q9BUL5	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	PHF23	Q9BUL5	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	PHF23	Q9BUL5	CYCS	Homo sapiens	P99999	Y2H Array	32814053
Intra	PHF23	Q9BUL5	CYCS	Homo sapiens	P99999	Validated Y2H	32814053
Intra	PHF23	Q9BUL5	CYCS	Homo sapiens	P99999	Y2H Pooling	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Myasthenic Syndrome, Congenital, 5

Endplate Acetylcholinesterase Deficiency	Congenital Myasthenic Syndrome 5
CMS5	Ead
Engel Congenital Myasthenic Syndrome	Myasthenic Syndrome, Congenital, Engel Type
Cms Ic	Congenital Myasthenic Syndrome Type Ic
Congenital Myasthenic Syndrome Type Ic, Formerly	Cms1c, Formerly
Cms Ic, Formerly	Congenital Myasthenic Syndrome Engel Type
End Plate Acetylcholinesterase Deficiency	Synaptic Congenital Myasthenic Syndromes
Cms1c	Cmse
Congenital Myasthenic Syndrome Type 1c	End-Plate Acetylcholinesterase Deficiency
Myasthenic Syndrome, Congenital, Type 5

Charcot-Marie-Tooth Disease, Axonal, Type 2e

Charcot-Marie-Tooth Disease Type 2	CMT2E
CMT2S	CMT2Y
Charcot-Marie-Tooth Disease Type 2e	Charcot-Marie-Tooth Disease Type 2y
Charcot-Marie-Tooth Disease Axonal Type 2s	Charcot-Marie-Tooth Disease, Axonal, Type 2s
Charcot-Marie-Tooth Disease, Type 2e	Hereditary Motor And Sensory Neuropathy Type 2
Charcot-Marie-Tooth Neuropathy, Type 2s	Charcot-Marie-Tooth Disease, Axonal, Autosomal Recessive, Type 2s
Charcot-Marie-Tooth Disease, Axonal, Type 2y	Charcot-Marie-Tooth Disease, Axonal, Autosomal Dominant, Type 2y
Charcot-Marie-Tooth Neuropathy, Type 2y	Charcot-Marie-Tooth Disease, Type 2y
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2e	Charcot-Marie-Tooth Neuropathy Type 2e
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 Due To Vcp Mutation	Cmt2 Due To Vcp Mutation
Charcot-Marie-Tooth Disease Type 2s	Autosomal Dominant Charcot-Marie-Tooth Disease Type 2
Autosomal Dominant Axonal Charcot-Marie-Tooth Disease	Cmt2
Charcot-Marie-Tooth Neuropathy, Type 2e	Hereditary Motor And Sensory Neuropathy Guadalajara Neuronal Type
Hereditary Motor And Sensory Neuropathy Okinawa Type	Autosomal Dominant Axonal Charcot-Marie-Tooth Type 2y
Charcot-Marie-Tooth Neuropathy Type 2y	Autosomal Recessive Axonal Charcot-Marie-Tooth Type 2s
Charcot-Marie-Tooth Neuropathy Type 2s	Charcot-Marie-Tooth Type 2
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2y	Charcot-Marie-Tooth Disease 2e
Charcot-Marie-Tooth Disease Axonal Type 2e	Charcot-Marie-Tooth Disease Neuronal Type 2e
Charcot-Marie-Tooth Disease 2s	Charcot-Marie-Tooth Neuropathy Axonal Type 2s
Charcot-Marie-Tooth Disease 2y	Charcot-Marie-Tooth Disease, Type 2
Hereditary Motor And Sensory-Neuropathy Type Ii

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10425	PHF23 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	PHF23	MGD	MGI:1925496
Macaca mulatta	PHF23	VGNC	VGNC:75877
Bos taurus	PHF23	VGNC	VGNC:32823
Canis familiaris	PHF23	VGNC	VGNC:44488
Rattus norvegicus	PHF23	RGD	RGD:1302969
Felis catus	PHF23	VGNC	VGNC:64144

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PHF23 - PHD finger protein 23 Gene

关于 PHF23

功能概要

PHF23 基因产物(3)

PHF23 蛋白结构

PHF23 蛋白互作信息

关联疾病

直系同源

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PHF23 - PHD finger protein 23 Gene

关于 PHF23

功能概要

PHF23 基因产物(3)

PHF23 蛋白结构

PHF23 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z