2. Gene
  3. Bhlhe41 - basic helix-loop-helix family, member e41 Gene

Bhlhe41 - basic helix-loop-helix family, member e41 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DEC2; Bhlhb3; Sharp1; Bhlhb2l; 6430520M22Rik

基因 ID: 79362 | 基因类型: protein coding

关于 Bhlhe41

功能概要

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with Arntl or compete for E-box binding sites in the promoter of Per1 and repress Clock/Arntl's transactivation of Per1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2014]

Bhlhe41 基因产物(2)

mRNA Protein Name
NM_001271768.1 NP_001258697.1 class E basic helix-loop-helix protein 41 isoform 2
NM_024469.2 NP_077789.1 class E basic helix-loop-helix protein 41 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12397359 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12397359 MGI
enables E-box binding IDA
IDA: 通过直接分析推断
12397359 MGI
enables MRF binding IDA
IDA: 通过直接分析推断
12657651 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12657651 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: 通过直接分析推断
17487425 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
12657651 MGI
enables bHLH transcription factor binding IDA
IDA: 通过直接分析推断
12657651 MGI
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
12397359 MGI
enables histone deacetylase binding IDA
IDA: 通过直接分析推断
17487425 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12397359 MGI
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
12397359 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
17487425 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian regulation of gene expression IMP
IMP: 通过突变表型推断
18411297 MGI
involved in circadian rhythm IEP
IEP: 通过表达模式推断
19786558 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12397359 MGI
involved in negative regulation of myotube differentiation IDA
IDA: 通过直接分析推断
12657651 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12397359 MGI
involved in negative regulation of transcription by competitive promoter binding IDA
IDA: 通过直接分析推断
12657651 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

class E basic helix-loop-helix protein 41

bHLH transcriptional factor Dec2

basic helix-loop-helix domain containing, class B3

class B basic helix-loop-helix protein 3

differentially expressed in chondrocytes protein 2

Bhlhe41 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Bhlhe41 Q99PV5 Cebpb Mus musculus P28033
Pull Down
19029947
Intra Bhlhe41 Q99PV5 Cebpb Mus musculus P28033
Anti Tag CoIP
19029947
Cross Bhlhe41 Q99PV5 PSMA4 Homo sapiens P25789
Anti Tag CoIP
22801492
Cross Bhlhe41 Q99PV5 HIF1A Homo sapiens Q16665
Anti Tag CoIP
22801492
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01494 BHLHE41 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bhlhe41 NCBI NCBI:79365
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