1. Gene
  2. RNF39 - ring finger protein 39 Gene

RNF39 - ring finger protein 39 Gene

中文名称:无名指蛋白 39

种属: Homo sapiens

同用名: HZF; HZFW; LIRF; FAP216

基因 ID: 80352 | 基因类型: protein coding

关于 RNF39

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,070,270-30,075,769 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 83 orthologues and 80 paralogues. Ubiquitous expression in small intestine (RPKM 5.5), duodenum (RPKM 5.3) and 25 other tissues.

功能概要

该基因位于 6 号染色体上的主要组织相容性复合体 I 类区域。对类似大鼠蛋白质的研究表明,该基因编码的蛋白质在突触可塑性的早期阶段发挥作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供,2008 年 7 月]

This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNF39 基因产物(2)

mRNA Protein Name
NM_025236.4 NP_079512.3 RING finger protein 39 isoform 1
NM_170769.3 NP_739575.3 RING finger protein 39 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RNF39 蛋白结构

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (88 - 134)

PRY

PRY: SPRY-associated domain (230 - 279)

SPRY

SPRY: SPRY domain (282 - 405)

  • 0
  • 100
  • 200
  • 300
  • 420 a.a.
蛋白主名 其他名称

RING finger protein 39

LTP (long-term potentiation) induced RING finger protein

RNF39 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RNF39 Q9H2S5 DNAAF6 Homo sapiens Q9NQM4
Validated Y2H
32296183
种属内
RNF39 Q9H2S5 DNAAF6 Homo sapiens Q9NQM4
Y2H Array
32296183
种属内
RNF39 Q9H2S5 DNAAF6 Homo sapiens Q9NQM4
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 AP1B1 Homo sapiens Q10567-3
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 AP1B1 Homo sapiens Q10567-3
Y2H Array
32296183
种属内
RNF39 Q9H2S5 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
种属内
RNF39 Q9H2S5 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 RABEP1 Homo sapiens Q15276
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 RABEP1 Homo sapiens Q15276
Y2H Array
32296183
种属内
RNF39 Q9H2S5 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
种属内
RNF39 Q9H2S5 RINT1 Homo sapiens Q6NUQ1
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 RINT1 Homo sapiens Q6NUQ1
Y2H Array
32296183
种属内
RNF39 Q9H2S5 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
32296183
种属内
RNF39 Q9H2S5 MORN3 Homo sapiens Q6PF18
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Psoriasis 10

PSORS10

Psoriasis Susceptibility 10

Psoriasis 10, Susceptibility To

Behcet Syndrome

Behcet Disease

Behcet'S Syndrome

Behcet'S Disease

Behçet Disease

Bd

Adamantiades-Behcet Disease

Triple Symptom Complex

Behçet'S Disease

Behet'S Syndrome

Bd Syndrome

Behçet Syndrome

Behçet'S Syndrome

Behcet Triple Symptom Complex

Malignant Aphthosis

Old Silk Route Disease

Adamantiades-Behçet Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus RNF39 VGNC VGNC:106899
Macaca mulatta RNF39 VGNC VGNC:83458
Rattus norvegicus RNF39 RGD RGD:628854
Canis familiaris RNF39 VGNC VGNC:54988
Mus musculus RNF39 MGD MGI:2156378