2. Gene
  3. SRCIN1 - SRC kinase signaling inhibitor 1 Gene

SRCIN1 - SRC kinase signaling inhibitor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SRC 激酶信号抑制因子 1

种属: Homo sapiens

同用名: P140; SNIP

基因 ID: 80725 | 基因类型: protein coding

关于 SRCIN1

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,530,031-38,607,025 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 282 orthologues and 1 paralogue. Biased expression in brain (RPKM 9.1), salivary gland (RPKM 1.2) and 2 other tissues.

功能概要

启用蛋白激酶结合活性。参与多个过程，包括树突棘形态发生的调节；调节蛋白酪氨酸激酶活性；和底物粘附依赖性细胞扩散。位于肌动蛋白细胞骨架和细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase binding activity. Involved in several processes, including regulation of dendritic spine morphogenesis; regulation of protein tyrosine kinase activity; and substrate adhesion-dependent cell spreading. Located in actin Cytoskeleton and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SRCIN1 基因产物(1)

mRNA Protein Name
NM_025248.3 NP_079524.2 SRC kinase signaling inhibitor 1
蛋白主名 其他名称

SRC kinase signaling inhibitor 1

P130Cas-associated protein

SRCIN1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SRCIN1 Q9C0H9 SRC Homo sapiens P12931
Anti Bait CoIP
17525734
种属内
SRCIN1 Q9C0H9 BCAR1 Homo sapiens P56945
Confocal
14657239
种属内
SRCIN1 Q9C0H9 BCAR1 Homo sapiens P56945
Anti Bait CoIP
14657239
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Maxillary Sinus Inverted Papilloma

Inverted Papilloma Of The Maxillary Sinus
Maxillary Sinus Benign Neoplasm

Neoplasm Of Maxillary Sinus

Tumor Of Maxillofacial Sinus

Maxillary Sinus Neoplasms

Maxillary Sinus Neoplasm
Frontal Sinus Inverted Papilloma

Inverted Papilloma Of The Frontal Sinus
Larynx Squamous Papilloma

Laryngeal Squamous Cell Papilloma
Frontal Sinus Benign Neoplasm

Neoplasm Of Frontal Sinus

Tumor Of The Frontal Sinus
Inverted Papilloma

Inverted Papilloma, Squamous Cell

Papilloma Inverted

Papilloma, Inverted

Inverted Squamous Cell Papilloma
Bipolar I Disorder

Manic Depression Nos

Manic-Depressive Illness

Bipolar Disorder Nos
Paranoid Personality Disorder
Schizoaffective Disorder

Schizo-Affective Psychosis

Schizo-Affective Type Schizophrenia

Schizoaffective Psychosis

Schizoaffective Schizophrenia

Schizophrenia, Schizo-Affective Type

Schizophreniform Psychosis, Affective Type
Kohlschutter-Tonz Syndrome

Amelocerebrohypohidrotic Syndrome

KTZS

Epilepsy And Yellow Teeth

Kohlschutter Tonz Syndrome

Kohlschutter Syndrome

Epilepsy Dementia Amelogenesis Imperfecta

Epilepsy-Dementia-Amelogenesis Imperfecta Syndrome

Epilepsy, Dementia, And Amelogenesis Imperfecta

Kohlschutter'S Syndrome

Kohlschütter-Tönz Syndrome

Kohlschuetter-Toenz Syndrome

Presenile Dementia

Dementia
Myopathy, Centronuclear, 2

Myopathy, Centronuclear, Autosomal Recessive

Autosomal Recessive Centronuclear Myopathy

CNM2

Centronuclear Myopathy 2

Ar-Cnm

Myotubular Myopathy, Autosomal Recessive

Autosomal Recessive Myotubular Myopathy

Centronuclear Myopathy Autosomal Recessive

Myopathy, Centronuclear, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16905 T338C Src-IN-1 Inhibitor / 否
HY-RS13753 SRCIN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SRCIN1 VGNC VGNC:78012
Mus musculus SRCIN1 MGD MGI:1933179
Canis familiaris SRCIN1 VGNC VGNC:46792
Bos taurus SRCIN1 VGNC VGNC:35270
Felis catus SRCIN1 VGNC VGNC:65672
Rattus norvegicus SRCIN1 RGD RGD:708439
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