2. Gene
  3. INTS14 - integrator complex subunit 14 Gene

INTS14 - integrator complex subunit 14 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：整合复合物亚基 14

种属: Homo sapiens

同用名: VWA9; C15orf44

基因 ID: 81556 | 基因类型: protein coding

关于 INTS14

This gene has 18 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in thyroid (RPKM 12.8), testis (RPKM 11.6) and 25 other tissues.

功能概要

预计参与 snRNA 3'端加工。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in snRNA 3'-end processing. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

INTS14 基因产物(10)

mRNA Protein Name
NM_001136043.3 NP_001129515.1 integrator complex subunit 14 isoform 1
NM_001207058.3 NP_001193987.2 integrator complex subunit 14 isoform 4
NM_001207059.3 NP_001193988.2 integrator complex subunit 14 isoform 1
NM_001366360.2 NP_001353289.1 integrator complex subunit 14 isoform 2
NM_001366364.2 NP_001353293.1 integrator complex subunit 14 isoform 1
NM_001366365.2 NP_001353294.1 integrator complex subunit 14 isoform 1
NM_001394794.1 NP_001381723.1 integrator complex subunit 14 isoform 2
NM_001394795.1 NP_001381724.1 integrator complex subunit 14 isoform 3
NM_001394796.1 NP_001381725.1 integrator complex subunit 14 isoform 2
NM_001394797.1 NP_001381726.1 integrator complex subunit 14 isoform 5
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24981860 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

INTS14 蛋白结构

VWA_2

VWA_2: von Willebrand factor type A domain (3 - 127)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
蛋白主名 其他名称

integrator complex subunit 14

UPF0464 protein C15orf44

INTS14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
INTS14 Q96SY0 INTS10 Homo sapiens Q9NVR2
Pull Down
32647223
种属内
INTS14 Q96SY0 INTS10 Homo sapiens Q9NVR2
Anti Tag CoIP
26496610
种属内
INTS14 Q96SY0 INTS13 Homo sapiens Q9NVM9
Anti Tag CoIP
26496610
种属内
INTS14 Q96SY0 INTS13 Homo sapiens Q9NVM9
Pull Down
32647223
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Folic Acid Deficiency Anemia

Folate Deficiency Anaemia

Folic Acid Deficiency Anaemia

Folate Deficiency Anemia

Folate-Deficiency Anaemia

Folate-Deficiency Anemia

Folate-Deficient Megaloblastic Anaemia

Megaloblastic Anemia Due To Folate Deficiency

Anaemia Of Folate Deficiency

Folate Or Folic Acid Deficiency Anaemia Nos

Folic Acid Deficiency Anaemia Nos

Acquired Megaloblastic Anaemia Due To Nutritional Folate Deficiency

Dietary Folic Acid Deficiency Anaemia

Dietary Folate Deficiency Anaemia

Folate Deficiency Anaemia Due To Dietary Causes

Goat'S Milk Anaemia

Acquired Megaloblastic Anaemia Due To Folate Deficiency Secondary To Increased Requirement

Megaloblastic Anaemia Due To Increased Requirements Of Folate

Acquired Megaloblastic Anaemia Due To Folate Deficiency Secondary To Intestinal Disorders

Acquired Megaloblastic Anaemia Due To Decreased Intestinal Absorption Of Folate

Megaloblastic Anaemia Due To Decreased Intestinal Absorption Of Folate
Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 4

SRTD4

Atd4

Jatd

Jeune Asphyxiating Thoracic Dystrophy

Jeune Syndrome 4
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06853 INTS14 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus INTS14 VGNC VGNC:30227
Macaca mulatta INTS14 VGNC VGNC:73650
Canis familiaris INTS14 VGNC VGNC:42050
Felis catus INTS14 VGNC VGNC:62942
Rattus norvegicus INTS14 RGD RGD:1359616
Mus musculus INTS14 MGD MGI:1917132
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