1. Gene
  2. LBH - LBH regulator of WNT signaling pathway Gene

LBH - LBH regulator of WNT signaling pathway Gene

中文名称:WNT 信号通路的 LBH 调节因子

种属: Homo sapiens

基因 ID: 81606 | 基因类型: protein coding

关于 LBH

Cytogenetic location: 2p23.1 Genomic coordinates (GRCh38): 2:30,231,534-30,260,028 (from NCBI)

This gene has 9 transcripts (splice variants), 190 orthologues and 1 paralogue. Broad expression in lung (RPKM 81.1), lymph node (RPKM 54.3) and 23 other tissues.

功能概要

参与转录的负调控,以 DNA 为模板;转录的正调控,DNA 模板化;和 MAPK 级联的调节。位于细胞质和细胞核中。部分含蛋白质复合物。 [由基因组资源联盟提供,2022 年 4 月]

Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of MAPK cascade. Located in cytoplasm and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

LBH 基因产物(1)

mRNA Protein Name
NM_030915.4 NP_112177.2 protein LBH
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20587334 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
20587334 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17390236 GOA
involved in regulation of MAPK cascade IMP
IMP: 通过突变表型推断
17390236 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17390236 GOA
located in nucleus IDA
IDA: 通过直接分析推断
17390236 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
20587334 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LBH 蛋白结构

Lbh

Lbh: Cardiac transcription factor regulator, Developmental protein (18 - 105)

  • 0
  • 105 a.a.
蛋白主名 其他名称

protein LBH

hLBH

直系同源

种属 基因名 来源 基因 ID
Felis catus LBH VGNC VGNC:81110
Bos taurus LBH VGNC VGNC:102824
Rattus norvegicus LBH RGD RGD:1584525
Mus musculus LBH MGD MGI:1925139