P2rx3 - purinergic receptor P2X 3 Gene

中文名称：嘌呤能受体 P2 X 3

种属: Rattus norvegicus

关于 P2rx3

功能概要

该基因编码的蛋白可启动多项功能，包括 ATP 绑定活动；细胞外 ATP 门控阳离子通道活性；和相同的蛋白质结合活性。涉及多个过程，包括对福尔马林引起的疼痛的行为反应；神经元动作电位；以及对疼痛感觉的正向调节。位于多个细胞成分中，包括树突棘；膜筏；和粗面内质网。是质膜的组成部分。是突触前膜的组成部分。与人 P2RX3（嘌呤能受体 P2X 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including ATP binding activity; extracellularly ATP-gated cation channel activity; and identical protein binding activity. Involved in several processes, including behavioral response to formalin induced pain; neuronal action potential; and positive regulation of sensory perception of pain. Located in several cellular components, including dendritic spine; membrane raft; and rough endoplasmic reticulum. Is integral component of plasma membrane. Is integral component of presynaptic membrane. Orthologous to human P2RX3 (purinergic receptor P2X 3). [provided by Alliance of Genome Resources, Apr 2022]