CAPZB - capping actin protein of muscle Z-line subunit beta Gene

中文名称：肌肉 Z 线亚基 beta 的封盖肌动蛋白

种属: Homo sapiens

同用名: CAPB; CAPZ; CAPPB

关于 CAPZB

功能概要

该基因编码倒刺末端肌动蛋白结合蛋白的 β 亚基，属于 F-肌动蛋白加帽蛋白家族。加帽蛋白是一种异源二聚体肌动蛋白加帽蛋白，可阻断肌动蛋白丝在快速生长 (倒刺) 丝末端的组装和分解，并在调节肌动蛋白丝动力学以及稳定肌肉和非肌肉细胞中的肌动蛋白丝长度方面发挥作用。该基因的一个假基因位于 2 号染色体的长臂上。已发现编码不同亚型的多个可变剪接转录本变体。[RefSeq 提供，2013 年 8 月]

This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Aug 2013]