2. Gene
  3. NRIP2 - nuclear receptor interacting protein 2 Gene

NRIP2 - nuclear receptor interacting protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核受体相互作用蛋白 2

种属: Homo sapiens

基因 ID: 83714 | 基因类型: protein coding

关于 NRIP2

This gene has 3 transcripts (splice variants), 174 orthologues and 4 paralogues. Ubiquitous expression in kidney (RPKM 4.3), ovary (RPKM 4.3) and 25 other tissues.

功能概要

预测启用天冬氨酸型内肽酶活性。预计参与蛋白水解。预计作用于 Notch 信号通路的上游或内部，并通过 RNA 聚合酶 II 负调控转录。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NRIP2 基因产物(1)

mRNA Protein Name
NM_031474.3 NP_113662.1 nuclear receptor-interacting protein 2

NRIP2 蛋白结构

Asp_protease

Asp_protease: Aspartyl protease (156 - 255)

  • 0
  • 100
  • 200
  • 281 a.a.
蛋白主名 其他名称

nuclear receptor-interacting protein 2

NRIP2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
Intra NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
Y2H Prey Pooling
32296183
Intra NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
Y2H Array
32296183
Intra NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
MAPPIT
32296183
Intra NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Temtamy Syndrome

TEMTYS

Craniofacial Dysmorphism With Ocular Coloboma Absent Corpus Callosum And Aortic Dilatation

Craniofacial Dysmorphism-Coloboma-Corpus Callosum Agenesis Syndrome

Dysmorphism, Corpus Callosum Agenesis And Colobomas

Temtamy-Shalash Syndrome

Mental Retardation With Or Without Craniofacial Dysmorphism, Ocular Coloboma, Or Abnormal Corpus Callosum
Sneddon Syndrome

Livedo Reticularis And Cerebrovascular Accidents

SNDNS

Ehrmann-Sneddon Syndrome

Livedo Racemosa-Cerebrovascular Accident Syndrome

Livedo Reticularis-Cerebrovascular Accident Syndrome

Sneddon'S Syndrome

Idiopathic Livedo Reticularis With Systemic Involvement

Cerebro-Vascular Lesions And Livedo Reticularis

Livedo Racemosa And Cerebrovascular Accidents
Cantu Syndrome

Hypertrichotic Osteochondrodysplasia

Hypertrichotic Osteochondrodysplasia Cantu Type

Cantú Syndrome

Craniofaciocardioskeletal Syndrome

Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome

Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum

Congenital Hypertrichosis-Coarse Facial Features Spectrum

HTOCD

Osteochondrodysplasia, Hypertrichotic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09572 NRIP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NRIP2 RGD RGD:1589959
Felis catus NRIP2 VGNC VGNC:63879
Bos taurus NRIP2 VGNC VGNC:59356
Macaca mulatta NRIP2 VGNC VGNC:75448
Mus musculus NRIP2 MGD MGI:1891884
Canis familiaris NRIP2 VGNC VGNC:43970
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