2. Gene
  3. Jam3 - junction adhesion molecule 3 Gene

Jam3 - junction adhesion molecule 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: JAM-3; JAM-C; Jcam3; 1110002N23Rik

基因 ID: 83964 | 基因类型: protein coding

关于 Jam3

功能概要

Enables identical protein binding activity and Integrin binding activity. Involved in angiogenesis; cell-cell adhesion; and hematopoietic stem cell migration to bone marrow. Acts upstream of or within several processes, including leukocyte migration involved in inflammatory response; myeloid progenitor cell differentiation; and regulation of actin Cytoskeleton organization by cell-cell adhesion. Located in Schmidt-Lanterman incisure; bicellular tight junction; and paranodal junction. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human JAM3 (junctional adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]

Jam3 基因产物(1)

mRNA Protein Name
NM_023277.4 NP_075766.1 junctional adhesion molecule C precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16093349 MGI
enables integrin binding IPI
IPI: 通过物理相互作用推断
16093349 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16093349 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adaptive immune response IMP
IMP: 通过突变表型推断
19342649 MGI
involved in angiogenesis IDA
IDA: 通过直接分析推断
15994945 MGI
acts upstream of or within cell adhesion IGI
IGI: 通过遗传相互作用推断
16093349 MGI
acts upstream of or within cell adhesion IMP
IMP: 通过突变表型推断
16093349 MGI
acts upstream of or within cell migration IDA
IDA: 通过直接分析推断
17099249 MGI
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
24357068 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
17099249 MGI
acts upstream of or within cell-matrix adhesion IGI
IGI: 通过遗传相互作用推断
17099249 MGI
acts upstream of or within establishment of cell polarity IDA
IDA: 通过直接分析推断
17099249 MGI
involved in hematopoietic stem cell migration to bone marrow IMP
IMP: 通过突变表型推断
24357068 MGI
acts upstream of or within leukocyte migration involved in inflammatory response IMP
IMP: 通过突变表型推断
15879142 MGI
acts upstream of or within myelination IMP
IMP: 通过突变表型推断
18048693 MGI
acts upstream of or within myeloid progenitor cell differentiation IMP
IMP: 通过突变表型推断
19109565 MGI
acts upstream of or within neutrophil homeostasis IMP
IMP: 通过突变表型推断
17455169 MGI
acts upstream of or within regulation of actin cytoskeleton organization by cell-cell adhesion IMP
IMP: 通过突变表型推断
15372036 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
15372036 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
15372036 MGI
acts upstream of or within transmission of nerve impulse IMP
IMP: 通过突变表型推断
18048693 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Schmidt-Lanterman incisure IDA
IDA: 通过直接分析推断
21097846 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
17853450 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
15372036 MGI
located in paranodal junction IDA
IDA: 通过直接分析推断
18048693 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

junctional adhesion molecule C

junction cell adhesion molecule 3

junction cell adhesion molecule C

junctional adhesion molecule 3

重组 Jam3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73849 JAM-C/CD323 Protein, Mouse (HEK293, His) Q9D8B7/NP_075766.1 (E30-N241) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07028 JAM3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jam3 NCBI NCBI:83700
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