1. Gene
  2. EVA1A - eva-1 homolog A, regulator of programmed cell death Gene

EVA1A - eva-1 homolog A, regulator of programmed cell death Gene

中文名称:eva-1 同系物 A,程序性细胞死亡的调节因子

种属: Homo sapiens

同用名: FAM176A; TMEM166

基因 ID: 84141 | 基因类型: protein coding

关于 EVA1A

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:75,492,318-75,569,719 (from NCBI)

This gene has 11 transcripts (splice variants), 263 orthologues and 1 paralogue. Biased expression in liver (RPKM 20.6), lung (RPKM 8.7) and 7 other tissues.

功能概要

预测参与细胞凋亡过程和自噬。位于细胞内膜结合的细胞器和质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in apoptotic process and Autophagy. Located in intracellular membrane-bounded organelle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVA1A 基因产物(4)

mRNA Protein Name
NM_001135032.2 NP_001128504.1 protein eva-1 homolog A
NM_001369524.1 NP_001356453.1 protein eva-1 homolog A
NM_001369525.1 NP_001356454.1 protein eva-1 homolog A
NM_032181.3 NP_115557.1 protein eva-1 homolog A
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

EVA1A 蛋白结构

FAM176

FAM176: FAM176 family (13 - 152)

  • 0
  • 100
  • 152 a.a.
蛋白主名 其他名称

protein eva-1 homolog A

family with sequence similarity 176, member A

EVA1A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EVA1A Q9H8M9 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
种属内
EVA1A Q9H8M9 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Fuchs' Endothelial Dystrophy

Fuchs Endothelial Corneal Dystrophy

Fuchs Endothelial Dystrophy

Fuchs Dystrophy

Fced

Fuchs' Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy

Fuchs Atrophy

Fuchs Corneal Dystrophy

Endoepithelial Corneal Dystrophy

Fecd

Late Hereditary Endothelial Dystrophy

Corneal Dystrophy, Fuchs Endothelial

Dystrophy, Corneal, Fuchs Endothelial

Corneal Dystrophy, Fuchs' Endothelial, 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta EVA1A VGNC VGNC:106159
Mus musculus EVA1A MGD MGI:2385247
Canis familiaris EVA1A VGNC VGNC:54943
Rattus norvegicus EVA1A RGD RGD:1559797