Sfrp1 - secreted frizzled-related protein 1 Gene

中文名称：分泌型卷曲相关蛋白 1

种属: Rattus norvegicus

同用名: sFRP-1

关于 Sfrp1

功能概要

预计该基因编码的蛋白具有多种功能，包括 Wnt 蛋白结合活性；卷曲的结合活动；和肝素结合活性。参与多个过程，包括细胞对前列腺素 E 刺激的反应；破骨细胞分化的负调节；和成骨细胞分化。预测位于细胞表面；含胶原蛋白的细胞外基质；和胞质溶胶。预计在细胞外空间活跃。与人类 SFRP1（分泌的卷曲相关蛋白 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including Wnt-protein binding activity; Frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to prostaglandin E stimulus; negative regulation of osteoclast differentiation; and osteoblast differentiation. Predicted to be located in cell surface; collagen-containing extracellular matrix; and cytosol. Predicted to be active in extracellular space. Orthologous to human SFRP1 (secreted Frizzled related protein 1). [provided by Alliance of Genome Resources, Apr 2022]