Il12a - interleukin 12A Gene

中文名称：白细胞介素 12A

种属: Rattus norvegicus

关于 Il12a

功能概要

预测该基因编码的蛋白可启动 interleukin-12 beta 亚基结合活性；白介素 27 结合活性；和蛋白质异二聚化活性。预计有助于细胞因子活性和生长因子活性。参与对粒细胞集落刺激因子的反应。预测位于细胞表面；细胞质；和细胞外空间。预计是白细胞介素 12 复合物的一部分。该基因与丙型肝炎有关的人类直系同源物；肝细胞癌；和原发性胆汁性胆管炎。与人 IL12A（白细胞介素 12A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable interleukin-12 beta subunit binding activity; interleukin-27 binding activity; and protein heterodimerization activity. Predicted to contribute to cytokine activity and growth factor activity. Involved in response to granulocyte colony-stimulating factor. Predicted to be located in cell surface; cytoplasm; and extracellular space. Predicted to be part of interleukin-12 complex. Human ortholog(s) of this gene implicated in hepatitis C; hepatocellular carcinoma; and primary biliary cholangitis. Orthologous to human IL12A (interleukin 12A). [provided by Alliance of Genome Resources, Apr 2022]