2. Gene
  3. ADGRG7 - adhesion G protein-coupled receptor G7 Gene

ADGRG7 - adhesion G protein-coupled receptor G7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：粘附 G 蛋白偶联受体 G7

种属: Homo sapiens

同用名: GPR128

基因 ID: 84873 | 基因类型: protein coding

关于 ADGRG7

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,609,601-100,695,479 (from NCBI)

This gene has 5 transcripts (splice variants), 193 orthologues and 42 paralogues. Biased expression in duodenum (RPKM 18.5), small intestine (RPKM 17.4) and 2 other tissues.

功能概要

预计可启用 G 蛋白偶联受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路。预计是膜的组成部分。预计是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ADGRG7 基因产物(2)

mRNA Protein Name
NM_001308362.1 NP_001295291.1 adhesion G-protein coupled receptor G7 isoform 2 precursor
NM_032787.3 NP_116176.2 adhesion G-protein coupled receptor G7 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ADGRG7 蛋白结构

GPS

GPS: GPCR proteolysis site, GPS, motif (380 - 422)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (433 - 715)

  • 0
  • 200
  • 400
  • 600
  • 797 a.a.
蛋白主名 其他名称

adhesion G-protein coupled receptor G7

G-protein coupled receptor 128

ADGRG7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ADGRG7 Q96K78 LDLRAD1 Homo sapiens Q5T700
Y2H Array
31515488
Intra ADGRG7 Q96K78 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
25416956
Intra ADGRG7 Q96K78 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra ADGRG7 Q96K78 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra ADGRG7 Q96K78 a8ka83_human Homo sapiens A8KA83
Y2H Prey Pooling
25416956
Intra ADGRG7 Q96K78 SORT1 Homo sapiens Q99523
Validated Y2H
32296183
Intra ADGRG7 Q96K78 SORT1 Homo sapiens Q99523
Y2H Prey Pooling
32296183
Intra ADGRG7 Q96K78 SORT1 Homo sapiens Q99523
Y2H Array
32296183
Intra ADGRG7 Q96K78 VAPA Homo sapiens Q9P0L0
Validated Y2H
32296183
Intra ADGRG7 Q96K78 VAPA Homo sapiens Q9P0L0
Y2H Array
32296183
Intra ADGRG7 Q96K78 VAPA Homo sapiens Q9P0L0
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Fibrogenesis Imperfecta Ossium

Baker'S Disease
Osteogenesis Imperfecta, Type Xvii

Osteogenesis Imperfecta Type 17

OI17

Osteogenesis Imperfecta Type Xvii

Osteogenesis Imperfecta 17
Osteogenesis Imperfecta, Type Iv

Osteogenesis Imperfecta Type 4

Osteogenesis Imperfecta Type Iv

OI4

Oi, Type Iv

Osteogenesis Imperfecta With Normal Sclerae

Oi Type Iv

Oi Type 4

Osteogenesis Imperfecta With Normal Sclera

Common Variable Oi With Normal Sclerae

Osteogenesis Imperfecta 4

Oi-Iv
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00360 ADGRG7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ADGRG7 MGD MGI:2441732
Canis familiaris ADGRG7 VGNC VGNC:37649
Bos taurus ADGRG7 VGNC VGNC:25670
Macaca mulatta ADGRG7 VGNC VGNC:69636
Rattus norvegicus ADGRG7 RGD RGD:1307217
Felis catus ADGRG7 VGNC VGNC:59637
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