1. Gene
  2. SSNA1 - SS nuclear autoantigen 1 Gene

SSNA1 - SS nuclear autoantigen 1 Gene

中文名称:SS 核自身抗原 1

种属: Homo sapiens

同用名: N14; NA14; NA-14

基因 ID: 8636 | 基因类型: protein coding

关于 SSNA1

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,188,676-137,190,366 (from NCBI)

This gene has 4 transcripts (splice variants) and 117 orthologues. Ubiquitous expression in testis (RPKM 42.7), kidney (RPKM 20.7) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计作用于参与平滑信号通路和纤毛内转运的纤毛受体簇的上游或内部。位于中心体。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Predicted to act upstream of or within ciliary receptor clustering involved in smoothened signaling pathway and intraciliary transport. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]

SSNA1 基因产物(1)

mRNA Protein Name
NM_003731.3 NP_003722.2 microtubule nucleation factor SSNA1
蛋白主名 其他名称

microtubule nucleation factor SSNA1

Sjogren syndrome nuclear autoantigen 1

SSNA1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SSNA1 O43805 TCEANC Homo sapiens Q8N8B7-2
Validated Y2H
32296183
Intra SSNA1 O43805 EHHADH Homo sapiens Q08426
Y2H Array
31515488
Intra SSNA1 O43805 EHHADH Homo sapiens Q08426
Y2H Prey Pooling
25416956
Intra SSNA1 O43805 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra SSNA1 O43805 RNF4 Homo sapiens P78317
Validated Y2H
32296183
Intra SSNA1 O43805 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Y2H
21516116
Intra SSNA1 O43805 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra SSNA1 O43805 LNX1 Homo sapiens Q8TBB1
Y2H Array
25416956
Intra SSNA1 O43805 TBC1D7 Homo sapiens Q9P0N9
Y2H Array
31515488
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Validated Y2H
27107012
Intra SSNA1 O43805 LNX1 Homo sapiens Q8TBB1
Y2H Array
29892012
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
32296183
Intra SSNA1 O43805 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
32296183
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Y2H
27107012
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Validated Y2H
32296183
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Y2H Array
25416956
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
SLC
27107012
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
BFG-2H
27107012
Intra SSNA1 O43805 SSNA1 Homo sapiens O43805
Y2H Array
32296183
Intra SSNA1 O43805 TXN2 Homo sapiens Q99757
Validated Y2H
25416956
Intra SSNA1 O43805 TXN2 Homo sapiens Q99757
Validated Y2H
32296183
Intra SSNA1 O43805 CDC37 Homo sapiens Q16543
Validated Y2H
32296183
Intra SSNA1 O43805 GOPC Homo sapiens Q9HD26
Y2H Prey Pooling
25416956
Intra SSNA1 O43805 GOPC Homo sapiens Q9HD26
Y2H Array
25416956
Intra SSNA1 O43805 LCA5 Homo sapiens Q86VQ0
TAP
27173435
Intra SSNA1 O43805 SDCBP Homo sapiens O00560
Validated Y2H
25416956
Intra SSNA1 O43805 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra SSNA1 O43805 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra SSNA1 O43805 TCEANC Homo sapiens Q8N8B7
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Paralytic Squint

Paralytic Strabismus

Incomitant Dissociation

Sjogren Syndrome

Sicca Syndrome

Sjogren'S Syndrome

Sjögren Syndrome

Sjogren-Gougerot Syndrome

Keratoconjunctivitis Sicca

Sjögren'S Syndrome

Xerodermosteosis

Dacryosialoadenopathia Atrophicans

Gougerot-Houwer-Sjogren Syndrome

Gougerot-Sjogren Syndrome

Keratoconjunctivitis Sicca-Xerostomia

Secreto-Inhibitor-Xerodermostenosis

Primary Sjogren Syndrome

Primary Sjogren-Gougerot Syndrome

Sjogrens Syndrome Primary

Sjogrens Syndrome

Dry Eye Syndromes

Spindle Cell Hemangioma

Sch

Spindle Cell Hemangioendothelioma

Hereditary Spastic Paraplegia

Familial Spastic Paraplegia

Hereditary Spastic Paraparesis

Strumpell-Lorrain Disease

Familial Spastic Paraparesis

Hsp

Spg

Strümpell-Lorrain Disease

Spastic Paraplegia, Hereditary

French Settlement Disease

Strumpell-Lorrain Syndrome

Fsp

Spastic Paraplegia, Familial

Spastic Paraplegia Hereditary

Spastic Paraplegia 3, Autosomal Dominant

Spastic Paraparesis

Hereditary Spastic Paralysis

Familial Spastic Paralysis

Hereditary Spastic Ataxia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SSNA1 VGNC VGNC:35316
Felis catus SSNA1 VGNC VGNC:65707
Mus musculus SSNA1 MGD MGI:1915725
Canis familiaris SSNA1 VGNC VGNC:46835
Rattus norvegicus SSNA1 RGD RGD:1310259