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  2. EIF3I - eukaryotic translation initiation factor 3 subunit I Gene

EIF3I - eukaryotic translation initiation factor 3 subunit I Gene

中文名称:真核翻译起始因子 3 亚基 I

种属: Homo sapiens

同用名: TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta

基因 ID: 8668 | 基因类型: protein coding

关于 EIF3I

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:32,222,407-32,236,170 (from NCBI)

This gene has 44 transcripts (splice variants) and 168 orthologues. Ubiquitous expression in thyroid (RPKM 51.3), ovary (RPKM 48.1) and 25 other tissues.

功能概要

有助于翻译起始因子活动。参与翻译起始。位于细胞外外泌体。真核翻译起始因子 3 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Contributes to translation initiation factor activity. Involved in translational initiation. Located in extracellular exosome. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]

EIF3I 基因产物(2)

mRNA Protein Name
NM_001394168.1 NP_001381097.1 eukaryotic translation initiation factor 3 subunit I isoform 2
NM_003757.4 NP_003748.1 eukaryotic translation initiation factor 3 subunit I isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14688252 GOA
contributes to translation initiation factor activity IDA
IDA: 通过直接分析推断
25849773 GOA
enables translation initiation factor activity IDA
IDA: 通过直接分析推断
17581632 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in translational initiation IDA
IDA: 通过直接分析推断
17581632 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of eukaryotic translation initiation factor 3 complex IDA
IDA: 通过直接分析推断
17322308 GOA
part of eukaryotic translation initiation factor 3 complex IPI
IPI: 通过物理相互作用推断
17322308 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

EIF3I 蛋白结构

WD40

WD40: WD domain, G-beta repeat (6 - 37)

WD40

WD40: WD domain, G-beta repeat (43 - 80)

WD40

WD40: WD domain, G-beta repeat (179 - 216)

WD40

WD40: WD domain, G-beta repeat (281 - 311)

  • 0
  • 100
  • 200
  • 300
  • 325 a.a.
蛋白主名 其他名称

eukaryotic translation initiation factor 3 subunit I

TGF-beta receptor-interacting protein 1

EIF3I 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EIF3I Q13347 CLEC4G Homo sapiens Q6UXB4
Anti Tag CoIP
18624398
种属内
EIF3I Q13347 CLEC4G Homo sapiens Q6UXB4
Confocal
18624398
种属内
EIF3I Q13347 CLEC4G Homo sapiens Q6UXB4
Y2H
18624398
种属内
EIF3I Q13347 EIF3G Homo sapiens O75821
Anti Tag CoIP
33961781
种属内
EIF3I Q13347 EIF3G Homo sapiens O75821
Anti Tag CoIP
35271311
种属内
EIF3I Q13347 EIF3B Homo sapiens P55884
Anti Tag CoIP
35271311
种属内
EIF3I Q13347 EIF3B Homo sapiens P55884
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Stomatitis
Clonorchiasis

Oriental Liver Fluke Disease

Clonorchis Liver Infection

Clonorchiosis

Chinese Liver Fluke Disease

Hepatic Distomiasis Due To Clonorchis Sinensis

Infection Due To Clonorchis Sinensis

Hepatic Distomiasis

Hepatic Distomatosis

Chinese Liver Fluke Disorder

Oriental Liver Fluke Disorder

Clonorchis Infestation

Chinese Liver Fluke Infestation

Liver Fluke Disease Due To Clonorchis Sinensis

Oriental Liver Fluke Infestation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus EIF3I MGD MGI:1860763
Felis catus EIF3I VGNC VGNC:61784
Canis familiaris EIF3I VGNC VGNC:40275
Macaca mulatta EIF3I VGNC VGNC:99897
Rattus norvegicus EIF3I RGD RGD:1584560
Bos taurus EIF3I VGNC VGNC:28399