1. Gene
  2. CBR3 - carbonyl reductase 3 Gene

CBR3 - carbonyl reductase 3 Gene

中文名称:羰基还原酶 3

种属: Homo sapiens

同用名: hCBR3; SDR21C2; HEL-S-25

基因 ID: 874 | 基因类型: protein coding

关于 CBR3

Cytogenetic location: 21q22.12 Genomic coordinates (GRCh38): 21:36,135,079-36,146,562 (from NCBI)

This gene has 1 transcript (splice variant), 503 orthologues and 13 paralogues. Ubiquitous expression in esophagus (RPKM 6.1), skin (RPKM 5.7) and 22 other tissues.

功能概要

羰基还原酶 3 催化大量具有生物和药理活性的羰基化合物还原为其相应的醇。该酶被归类为单体 NADPH 依赖性氧化还原酶。 CBR3 包含三个跨越 11.2 千碱基的外显子,并与另一个羰基还原酶基因 - CBR1 密切相关。[RefSeq 提供,2008 年 7 月]

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The Enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

CBR3 基因产物(1)

mRNA Protein Name
NM_001236.4 NP_001227.1 carbonyl reductase [NADPH] 3

CBR3 蛋白结构

adh_short

adh_short: short chain dehydrogenase (7 - 147)

  • 0
  • 100
  • 200
  • 277 a.a.
蛋白主名 其他名称

carbonyl reductase [NADPH] 3

NADPH-dependent carbonyl reductase 3

重组 CBR3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75605 CBR3 Protein, Human (His) O75828 (M1-W277) ≥95%

直系同源

种属 基因名 来源 基因 ID
Mus musculus CBR3 MGD MGI:1309992
Bos taurus CBR3 VGNC VGNC:53516
Rattus norvegicus CBR3 RGD RGD:1309728
Canis familiaris CBR3 VGNC VGNC:38764
Felis catus CBR3 VGNC VGNC:102611
Others CBR3 NCBI