2. Gene
  3. CDC123 - cell division cycle 123 Gene

CDC123 - cell division cycle 123 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞分裂周期 123

种属: Homo sapiens

同用名: D123; C10orf7

基因 ID: 8872 | 基因类型: protein coding

关于 CDC123

Cytogenetic location: 10p14-p13 Genomic coordinates (GRCh38): 10:12,196,188-12,250,589 (from NCBI)

This gene has 9 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in lymph node (RPKM 28.2), appendix (RPKM 26.4) and 25 other tissues.

功能概要

预计参与真核翻译起始因子 2 复合物组装和翻译起始的正调控。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in eukaryotic translation initiation factor 2 complex assembly and positive regulation of translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CDC123 基因产物(1)

mRNA Protein Name
NM_006023.3 NP_006014.2 cell division cycle protein 123 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
37507029 GOA
enables magnesium ion binding IDA
IDA: 通过直接分析推断
37507029 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in eukaryotic translation initiation factor 2 complex assembly IDA
IDA: 通过直接分析推断
37507029 GOA
involved in eukaryotic translation initiation factor 2 complex assembly IMP
IMP: 通过突变表型推断
37507029 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10942595 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CDC123 蛋白结构

D123

D123: D123 (14 - 315)

  • 0
  • 100
  • 200
  • 300
  • 336 a.a.
蛋白主名 其他名称

cell division cycle protein 123 homolog

HT-1080

CDC123 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CDC123 O75794 EIF2S2 Homo sapiens P20042
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Wolfram Syndrome 1

WFS1

Didmoad

Wfs

Diabetes Mellitus And Insipidus With Optic Atrophy And Deafness

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Syndrome

Wolfram Syndrome
Wolfram Syndrome

Didmoad Syndrome

Didmoad

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Wfs

Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness

Didmoadud

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome
Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset
Diabetes Mellitus

Diabetes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02284 CDC123 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CDC123 RGD RGD:619766
Bos taurus CDC123 VGNC VGNC:27058
Felis catus CDC123 VGNC VGNC:83521
Mus musculus CDC123 MGD MGI:2138811
Canis familiaris CDC123 VGNC VGNC:38985
Macaca mulatta CDC123 VGNC VGNC:70768
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