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  2. BUD31 - BUD31 homolog Gene

BUD31 - BUD31 homolog Gene

中文名称:BUD31 同系物

种属: Homo sapiens

同用名: G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W

基因 ID: 8896 | 基因类型: protein coding

关于 BUD31

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:99,408,969-99,419,616 (from NCBI)

This gene has 9 transcripts (splice variants) and 222 orthologues. Ubiquitous expression in testis (RPKM 25.3), bone marrow (RPKM 23.9) and 25 other tissues.

功能概要

启用核受体结合活性和核受体共激活因子活性。参与 mRNA 剪接,通过剪接体和雄激素受体活性的正调节。位于核内。 U2 型催化步骤 2 剪接体的一部分。与染色质共定位。 [由基因组资源联盟提供,2022 年 4 月]

Enables nuclear receptor binding activity and nuclear receptor coactivator activity. Involved in mRNA splicing, via spliceosome and positive regulation of Androgen Receptor activity. Located in nucleus. Part of U2-type catalytic step 2 spliceosome. Colocalizes with chromatin. [provided by Alliance of Genome Resources, Apr 2022]

BUD31 基因产物(3)

mRNA Protein Name
NM_001370407.1 NP_001357336.1 protein BUD31 homolog
NM_001370410.1 NP_001357339.1 protein BUD31 homolog
NM_003910.4 NP_003901.2 protein BUD31 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nuclear receptor binding IDA
IDA: 通过直接分析推断
25091737 GOA
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
25091737 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25091737 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
28076346 GOA
involved in positive regulation of androgen receptor activity IDA
IDA: 通过直接分析推断
25091737 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of U2-type catalytic step 2 spliceosome IDA
IDA: 通过直接分析推断
28076346 GOA
located in chromatin IDA
IDA: 通过直接分析推断
25091737 GOA
located in nucleus IDA
IDA: 通过直接分析推断
28076346 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BUD31 蛋白结构

G10

G10: G10 protein (1 - 143)

  • 0
  • 100
  • 144 a.a.
蛋白主名 其他名称

protein BUD31 homolog

G10 maternal transcript homolog

BUD31 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Validated Y2H
32296183
Intra BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra BUD31 P41223 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra BUD31 P41223 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra BUD31 P41223 HOXA1 Homo sapiens P49639
Validated Y2H
32296183
Intra BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus BUD31 VGNC VGNC:26609
Macaca mulatta BUD31 VGNC VGNC:70441
Mus musculus BUD31 MGD MGI:2141291
Rattus norvegicus BUD31 RGD RGD:621103
Felis catus BUD31 VGNC VGNC:60213