2. Gene
  3. TNFSF18 - TNF superfamily member 18 Gene

TNFSF18 - TNF superfamily member 18 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：TNF 超家族成员 18

种属: Homo sapiens

同用名: TL6; AITRL; GITRL; TNLG2A; hGITRL

基因 ID: 8995 | 基因类型: protein coding

关于 TNFSF18

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:173,039,202-173,050,941 (from NCBI)

This gene has 1 transcript (splice variant) and 83 orthologues. Broad expression in gall bladder (RPKM 1.2), brain (RPKM 1.0) and 16 other tissues.

功能概要

该基因编码的蛋白质是一种属于肿瘤坏死因子 (TNF) 配体家族的细胞因子。这种细胞因子是受体 TNFRSF18/AITR/GITR 的配体。它已被证明可以调节外周组织中的 T 淋巴细胞存活。还发现这种细胞因子在内皮细胞中表达，并且被认为对 T 淋巴细胞和内皮细胞之间的相互作用很重要。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]

TNFSF18 基因产物(1)

mRNA Protein Name
NM_005092.4 NP_005083.3 tumor necrosis factor ligand superfamily member 18

TNFSF18 蛋白结构

TNF

TNF: TNF(Tumour Necrosis Factor) family (103 - 192)

  • 0
  • 100
  • 199 a.a.
蛋白主名 其他名称

tumor necrosis factor ligand superfamily member 18

AITR ligand

重组 TNFSF18 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7318 AITRL/TNFSF18 Protein, Human Q9UNG2 (E52-I176) ≥95%
HY-P74503 AITRL/TNFSF18 Protein, Human (sf9, His) Q9UNG2/AAD22634 (E52-S177) ≥95%
HY-P76110 AITRL/TNFSF18 Protein, Human (HEK293, Fc) Q9UNG2/NP_005083.3 (Q50-S177) ≥95%
HY-P78133 AITRL/TNFSF18 Trimer Protein, Human (Biotinylated, HEK293, His-Flag) Q9UNG2 (Q50-S177) ≥95%
HY-P78448 AITRL/TNFSF18 Trimer Protein, Human (HEK293, His-Flag) Q9UNG2 (Q50-S177) ≥95%
HY-P700014AF Animal-Free AITRL/TNFSF18 Protein, Human (His) Q9UNG2 (Q49-I174) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14827 TNFSF18 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TNFSF18 VGNC VGNC:36175
Felis catus TNFSF18 VGNC VGNC:107953
Canis familiaris TNFSF18 VGNC VGNC:53841
Macaca mulatta TNFSF18 VGNC VGNC:78597
Mus musculus TNFSF18 MGD MGI:2673064
Rattus norvegicus TNFSF18 RGD RGD:1305066
Macaca fascicularis TNFSF18 NCBI NCBI:102140808
Others TNFSF18 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z