ARHGEF1 - Rho guanine nucleotide exchange factor 1 Gene

中文名称：Rho 鸟嘌呤核苷酸交换因子 1

种属: Homo sapiens

同用名: LSC; GEF1; IMD62; LBCL2; SUB1.5; P115-RHOGEF

关于 ARHGEF1

功能概要

Rho GTP 酶在许多细胞过程中起着重要作用，这些过程由通过 G 蛋白偶联受体起作用的细胞外刺激物启动。编码的蛋白质可能与 G 蛋白形成复合物并刺激 Rho 依赖性信号。已发现该基因的多个可变剪接转录本变体，但尚未确定某些变体的全长性质。[RefSeq 提供，2008 年 7 月]

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]