1. Gene
  2. CD7 - CD7 molecule Gene

CD7 - CD7 molecule Gene

中文名称:CD7 分子

种属: Homo sapiens

同用名: GP40; TP41; Tp40; LEU-9

基因 ID: 924 | 基因类型: protein coding

关于 CD7

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,314,873-82,317,608 (from NCBI)

This gene has 7 transcripts (splice variants) and 89 orthologues. Biased expression in spleen (RPKM 5.2), appendix (RPKM 4.1) and 12 other tissues.

功能概要

该基因编码一种跨膜蛋白,它是免疫球蛋白超家族的成员。这种蛋白质存在于胸腺细胞和成熟 T 细胞中。它在 T 细胞相互作用以及早期淋巴发育过程中的 T 细胞/B 细胞相互作用中起着重要作用。[RefSeq 提供,2008 年 7 月]

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]

CD7 基因产物(1)

mRNA Protein Name
NM_006137.7 NP_006128.1 T-cell antigen CD7 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
enables transmembrane signaling receptor activity IDA
IDA: 通过直接分析推断
10652336 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of T cell cytokine production IDA
IDA: 通过直接分析推断
10652336 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CD7 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (27 - 131)

  • 0
  • 100
  • 200
  • 240 a.a.
蛋白主名 其他名称

T-cell antigen CD7

CD7 antigen (p41)

CD7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CD7 P09564 PTRH2 Homo sapiens Q9Y3E5
Anti Tag CoIP
33961781
种属内
CD7 P09564 PTRH2 Homo sapiens Q9Y3E5
Anti Tag CoIP
28514442
种属内
CD7 P09564 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70497 CD7 Protein, Human (HEK293, His) P09564 (A26-P180) ≥95%
HY-P72361 CD7 Protein, Human (Biotinylated, HEK293, His-Avi) P09564 (A26-P180) ≥95%
HY-P78414 CD7 Protein, Human (HEK293, His-Avi) P09564 (A26-P180) ≥95%
HY-P700854 CD7 Protein, Human (HEK293, hFc) P09564 (A26-P180) ≥95%

关联疾病

疾病名称 别名
Mycosis Fungoides

Mycosis Fungoides Lymphoma

Alibert-Bazin Syndrome

Granuloma Fungoides

Classic Mycosis Fungoides

Mycosis Fungoides, Alibert-Bazin Type

Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic

Lymphoma Lymphoblastic

Precursor Cell Lymphoblastic Lymphoma

Precursor Cell Lymphoblastic Leukemia Lymphoma

Follicular Mucinosis

Alopecia Mucinosa

Mucinosis, Follicular

Mixed Phenotype Acute Leukemia, T/Myeloid

Doid:0081039

Sezary'S Disease

Sezary Syndrome

Sézary Syndrome

Sezary'S Lymphoma

Sezary Disease

Sezary Erythroderma

Sezary Lymphoma

Strongyloidiasis

Disseminated Strongyloidiasis

Anguilluliasis

Anguillulosis

Infection By Strongyloides

Threadworm Infection

Enterobiasis

Parapsoriasis

Digitate Dermatosis

Parapsoriasis En Plaque

Parapsoriasis En Plaques

Acute Leukemia

Stem Cell Leukaemia

Stem Cell Leukemia

Acute Leukemias

Acute Undifferentiated Leukemia

Undifferentiated Leukemia

Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission

Blast Cell Leukaemia

Blast Leukaemia

Blastic Leukaemia

Undifferentiated Leukaemia

T-Cell Adult Acute Lymphocytic Leukemia

Acute Adult T-Cell Leukemia-Lymphoma

Adult Precursor T Lymphoblastic Leukemia

Atll

T-Cell Adult Acute Lymphoblastic Leukemia

Aggressive Nk-Cell Leukemia

Aggressive Nk-Cell Leukaemia

Large Granular Lymphocyte Leukemia, Nk-Cell Type

Natural Killer Cell Leukaemia

Natural Killer Cell Leukemia

Aggressive Nk Cell Leukemia

Ankl

Aggressive Natural Killer Cell Leukemia

Ankcl

Aggressive Nk-Cell Lymphoma

Nk-Cell Lgl Leukemia

Nk-Cell Large Granular Lymphocyte Leukemia

Abnormality Of The Ankles

Aggressive Natural Killer-Cell Leukemia

Leukemia, Large Granular Lymphocytic

Leukemia, Natural Killer Cell Large Granular Lymphocytic

Primary Cutaneous Gamma-Delta T-Cell Lymphoma

Cutaneous Gamma/Delta T-Cell Lymphoma

Primary Cutaneous Gamma-Delta T Cell Lymphomas

Doid:0081050

Hepatosplenic T-Cell Lymphoma

Doid:0081049

Mature T-Cell And Nk-Cell Lymphoma

Mature T-Cell And Natural Killer Cell Lymphoma

Nk-T Cell Lymphoma

Rectum Lymphoma

Lymphoma Of Rectum

Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos

Spongiotic Dermatitis
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

T-Cell Prolymphocytic Leukemia

T Cell Prolymphocytic Leukemia

Prolymphocytic Leukemia, T-Cell Type

T-Pll

T-Cell Chronic Lymphocytic Leukemia

Lymphocytic Leukemia T-Cell Chronic

Doid:0081042

Leukemia, T-Cell, Chronic

Prolymphocytic Leukaemia Of T-Cell Type Without Mention Of Remission

Inflammatory Bowel Disease 16

IBD16

Inflammatory Bowel Disease 16, Susceptibility To

Acute Biphenotypic Leukemia

Mixed Phenotype Acute Leukemia

Acute Leukemia Of Ambiguous Lineage

Acute Undifferentiated Leukemia

Acute Leukemia Of Indeterminate Lineage

Hybrid Acute Leukemia

Mixed Lineage Acute Leukemia

All With Myeloid Markers

Aml With Lymphoid Markers

Acute Leukemia Of Undetermined Lineage

Bal

Biphenotypic Acute Leukemia

Undifferentiated Acute Leukemia

Mpal

Acute Myeloid Leukemia, Minimal Differentiation, Fab M0

Leukemia, Biphenotypic, Acute

Breast Implant-Associated Anaplastic Large Cell Lymphoma
Adult Acute Lymphocytic Leukemia

Adult Acute Lymphoid Leukemia

Adult All

Disseminated Eosinophilic Collagen Disease
Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3

T-Cell Large Granular Lymphocyte Leukemia

Large Granular Lymphocytic Leukemia

Proliferation Of Large Granular Lymphocytes

T-Lgl

T-Cell Lgl Leukemia

Large Granular Lymphocytic Leukaemia

T-Cell Large Granular Lymphocyte Leukaemia

Large Cell Granular Lymphogenous Leukemia

T-Lgl Leukemia

Leukemia Lymphocytic Large Granular

Leukemia, Large Granular Lymphocytic

Lethal Midline Granuloma

Granuloma, Lethal Midline

Malignant Granuloma Of Face

Midfacial Necrotising Lesion

Midline Lethal Granuloma

B-Lymphoblastic Leukemia/Lymphoma With Hypodiploidy

B-All With Hypodiploidy

Hypodiploid All

Adult T-Cell Leukemia/Lymphoma

Adult T-Cell Leukemia

Atll

Adult T-Cell Leukaemia

Adult T-Cell Leukaemia/Lymphoma

Adult T-Cell Lymphoma

T Cell Leukemia Lymphoma Adult

Leukemia-Lymphoma, Adult T-Cell

Leukemia, T-Cell

Adult T-Cell Lymphoma/Leukemia

Myeloproliferative Syndrome, Transient

Transient Abnormal Myelopoiesis

Transient Myeloproliferative Syndrome

Transient Myeloproliferative Disease

Mst

Tam

Leukemia, Transient, Of Down Syndrome

Tmd

Leukemia, Transient

Transient Leukemia

Transient Leukemia Of Down Syndrome

Angioimmunoblastic T-Cell Lymphoma

Immunoblastic Lymphadenopathy

Lymphogranulomatosis X

T-Cell Lymphoma, Aild Type

Aitl

Ailt

Angioimmunoblastic Lymphadenopathy

Aild - [Angioimmunoblastic Lymphadenopathy With Dysproteinaemia]

Angioimmunoblastic Lymphoma

Central Nervous System Leukemia

Leukemia Of The Cns

Chronic Nk-Cell Lymphocytosis

Nk-Cell Large Granular Lymphocyte Lymphocytosis

Chronic Lymphoproliferative Disorder Of Nk-Cells

Myeloid Sarcoma

Granulocytic Sarcoma

Chloroma

Extramedullary Myeloid Tumor

Sarcoma, Granulocytic

Sarcoma Granulocytic

Sarcoma, Myeloid

Myelosarcoma

Myeloid Sarcoma Disease

Myeloid Sarcoma Nos

Myeloid Sarcoma Without Mention Of Remission

Prolymphocytic Leukemia

Pll

Prolymphocytic Leukaemia

Leukemia Prolymphocytic

Leukemia, Prolymphocytic

Intrahepatic Bile Duct Adenoma

Adenoma Of Intrahepatic Bile Duct

Adenoma Of The Intrahepatic Bile Duct

Mesothelioma, Malignant

Malignant Mesothelioma

Pleural Mesothelioma

MESOM

Mesothelioma, Somatic

Advanced Malignant Mesothelioma

Asbestos-Related Malignant Mesothelioma

Diffuse Malignant Mesothelioma

Malignant Tumor Of Mesothelium

Malignant Mesothelioma, Susceptibility To

Mesothelioma Diffuse Malignant

Mesothelioma

Malignant Pleural Mesothelioma

Peripheral T-Cell Lymphoma

Lymphoma T-Cell Peripheral

Childhood T-Cell Acute Lymphoblastic Leukemia

T-Cell Childhood Acute Lymphoblastic Leukemia

Childhood Precursor T-Lymphoblastic Lymphoma/Leukemia

T-Cell Childhood Acute Lymphocytic Leukemia

Childhood T Lymphoblastic Leukemia/Lymphoma

Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

Cutaneous T-Cell Lymphoma

Cutaneous T Cell Lymphoma

Lymphoma, T-Cell, Cutaneous

Ctcl

Lymphoma T-Cell Cutaneous

Paranasal Sinus Lymphoma

Lymphoma Of Accessory Sinus

Lymphoma Of Paranasal Sinus

Precursor T-Cell Acute Lymphoblastic Leukemia

T-All

Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Precursor T-Cell Acute Lymphocytic Leukemia

Precursor T-Cell Acute Lymphocytic Leukemia/Lymphoma

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Adult T-Cell Lymphoma/Leukemia

Anal Paget'S Disease

Anal Paget Disease

Paget'S Disease Of Anus

Paget'S Disease Of The Anus

Paget Disease Of The Anus

B-Lymphoblastic Leukemia/Lymphoma

B Lymphoblastic Leukemia/Lymphoma

B-All

Precursor B Lymphoblastic Lymphoma/Leukemia

C-All

Lymphoblastic Lymphoma, Nos

Common Precursor B All

Lymphoblastic B-Cell Lymphoma

Pro-B All

B-Precursor Lymphoma

Lbl - [Lymphoblastic Lymphoma]

Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia

Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Acute Megakaryocytic Leukemia

Acute Megakaryoblastic Leukemia

Acute Megakaryoblastic Leukaemia

Megakaryocytic Myelosis

Thrombocytic Leukaemia

Amkl

Aml M7

Acute Myeloblastic Leukemia Type 7

Acute Myeloid Leukemia M7

Megakaryoblastic Leukemia Acute

Leukemia, Megakaryoblastic, Acute

Acute Myeloid Leukaemia, M7

Acute Megakaryocytic Leukaemia

Acute Megakaryoblastic Leukaemia, Fab M7

Fab M7

Malignant Megakaryocytosis

M7 - Acute Megakaryoblastic Leukaemia

Megakaryoblastic Leukaemia

Megakaryocytic Leukaemia

Acute Megakaryoblastic Leukaemia, Nos

Acute Megakaryoblastic Leukaemia Without Mention Of Remission

Pancytopenia
Appendix Lymphoma

Appendiceal Lymphoma

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Celiac Disease 1

Celiac Disease

Coeliac Disease

Celiac Sprue

Celiac Disease, Susceptibility To

Gluten-Sensitive Enteropathy

Nontropical Sprue

Sprue

CELIAC1

Celiac Disease, Susceptibility To, 1

Celiac Sprue 1

Celiac Sprue, Susceptibility To, 1

Gluten-Sensitive Enteropathy 1

Gluten-Sensitive Enteropathy, Susceptibility To, 1

Idiopathic Steatorrhea

Cœliac Disease

Gluten Intolerance

Gluten-Induced Enteropathy

Gluten Enteropathy

Celiac Disease, Susceptibility To, Type 1

Childhood Celiac Disease

Coeliac Rickets

Gee Disease

Gee-Herter Disease

Heubner-Herter Disease

Idiopathic Steatorrhoea

Thaysen'S Disease

Herter Gee Syndrome

Myelodysplastic Syndrome

Myelodysplastic Syndromes

Myelodysplasia

MDS

Myelodysplastic Syndrome Included

Myelodysplastic Syndrome, Susceptibility To, Included

Myelodysplastic Syndrome, Somatic

Myelodysplastic Syndrome, Susceptibility To

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CD7 MGD MGI:88344
Rattus norvegicus CD7 RGD RGD:1310015
Bos taurus CD7 VGNC VGNC:27044
Canis familiaris CD7 VGNC VGNC:38969
Macaca mulatta CD7 VGNC VGNC:104593
Felis catus CD7 VGNC VGNC:98785
Macaca fascicularis CD7 NCBI NCBI:102124399
Others CD7 NCBI