2. Gene
  3. BPIFB1 - BPI fold containing family B member 1 Gene

BPIFB1 - BPI fold containing family B member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 BPI 折叠家族 B 成员 1

种属: Homo sapiens

同用名: LPLUNC1; C20orf114

基因 ID: 92747 | 基因类型: protein coding

关于 BPIFB1

This gene has 3 transcripts (splice variants), 93 orthologues and 12 paralogues. Biased expression in stomach (RPKM 277.8), lung (RPKM 49.9) and 2 other tissues.

功能概要

该基因编码的蛋白质可能参与对口腔、鼻腔和肺部细菌暴露的先天免疫反应。编码的蛋白质是分泌型的，是 BPI/LBP/PLUNC 蛋白质超家族的成员。该基因在 20 号染色体上的簇中与超家族的其他成员一起被发现。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene may be involved in the innate immune response to Bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with Other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]

BPIFB1 基因产物(1)

mRNA Protein Name
NM_033197.3 NP_149974.2 BPI fold-containing family B member 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in innate immune response in mucosa IDA
IDA: 通过直接分析推断
21900486 GOA
involved in negative regulation of toll-like receptor 4 signaling pathway IDA
IDA: 通过直接分析推断
21900486 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
20237794 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BPIFB1 蛋白结构

LBP_BPI_CETP

LBP_BPI_CETP: LBP / BPI / CETP family, N-terminal domain (44 - 209)

LBP_BPI_CETP_C

LBP_BPI_CETP_C: LBP / BPI / CETP family, C-terminal domain (363 - 457)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 484 a.a.
蛋白主名 其他名称

BPI fold-containing family B member 1

VEMSGP

重组 BPIFB1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76178 BPIFB1 Protein, Human (HEK293, His) Q8TDL5 (T22-Q484) ≥95%

关联疾病

疾病名称 别名
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Papillary Cystadenocarcinoma

Cystadenocarcinoma, Papillary
Autoimmune Polyendocrine Syndrome Type 1

Whitaker Syndrome

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

Autoimmune Polyglandular Syndrome I

Polyglandular Type I Autoimmune Syndrome
Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01583 BPIFB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus BPIFB1 VGNC VGNC:26545
Felis catus BPIFB1 VGNC VGNC:60155
Macaca mulatta BPIFB1 VGNC VGNC:107774
Canis familiaris BPIFB1 VGNC VGNC:38507
Mus musculus BPIFB1 MGD MGI:2137431
Rattus norvegicus BPIFB1 RGD RGD:1563047
Others BPIFB1 NCBI
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