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  3. BPIFB1 蛋白, Human (HEK293, His)

BPIFB1 蛋白, Human (HEK293, His)

目录号: HY-P76178
产品使用指南

BPIFB1 蛋白可能在抵抗微生物威胁的先天免疫中发挥着至关重要的作用,特别是在口、鼻和肺中。它与细菌脂多糖 (LPS) 结合,调节细胞反应并影响 LPS 触发的免疫信号通路。BPIFB1 蛋白, Human (HEK293, His) 是重组的 BPIFB1 蛋白,由 HEK293 表达,带有 C-His 标签。BPIFB1 蛋白, Human (HEK293, His) 全长 463 个氨基酸,分子量约为 ~53 KDa。

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描述

The BPIFB1 protein may play a crucial role in innate immunity, particularly in the mouth, nose, and lungs, against microbial threats. It binds to bacterial lipopolysaccharide (LPS), modulates cellular responses and affects LPS-triggered immune signaling pathways. BPIFB1 Protein, Human (HEK293, His) is the recombinant human-derived BPIFB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of BPIFB1 Protein, Human (HEK293, His) is 463 a.a., with molecular weight of ~53 KDa.

研究背景

BPIFB1 蛋白被认为在先天免疫中发挥着至关重要的作用,特别是在口、鼻和肺区域,突显了其在防御粘膜表面微生物威胁方面的重要性。从功能上讲,BPIFB1 已知可结合细菌脂多糖 (LPS)(细菌细胞壁的关键成分),并调节细胞对 LPS 的反应。这种相互作用意味着 BPIFB1 通过影响 LPS 触发的细胞信号通路来调节对细菌感染的免疫反应。BPIFB1 促进先天免疫的具体机制及其在粘膜防御中的精确作用仍然是人们感兴趣的领域,这强调需要进一步研究以阐明其在上呼吸道和口腔区域免疫防御背景下的功能和分子相互作用。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

Q8TDL5 (T22-Q484)

基因 ID
蛋白结构
N-term
BPIFB1 (T22-Q484)
Accession # Q8TDL5
His
C-term
同用名
BPI fold-containing family B member 1; VEMSGP; BPIFB1; C20orf114; LPLUNC1
分子量

Approximately 53 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

BPIFB1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
BPIFB1 Protein, Human (HEK293, His)
目录号:
HY-P76178
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