2. Gene
  3. CD83 - CD83 molecule Gene

CD83 - CD83 molecule Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CD83 分子

种属: Homo sapiens

同用名: BL11; HB15

基因 ID: 9308 | 基因类型: protein coding

关于 CD83

Cytogenetic location: 6p23 Genomic coordinates (GRCh38): 6:14,117,256-14,136,918 (from NCBI)

This gene has 2 transcripts (splice variants) and 120 orthologues. Broad expression in bone marrow (RPKM 72.2), lymph node (RPKM 25.8) and 14 other tissues.

功能概要

由该基因编码的蛋白质是一种单程 I 型膜蛋白，是免疫球蛋白受体超家族的成员。编码的蛋白质可能参与抗原呈递的调节。这种蛋白质的可溶形式可以与树突细胞结合并抑制它们的成熟。已发现该基因的三个转录变体编码不同的亚型。[RefSeq 提供，2011 年 10 月]

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

CD83 基因产物(3)

mRNA Protein Name
NM_001040280.3 NP_001035370.1 CD83 antigen isoform b precursor
NM_001251901.1 NP_001238830.1 CD83 antigen isoform c
NM_004233.4 NP_004224.1 CD83 antigen isoform a precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20374249 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CD83 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (20 - 119)

  • 0
  • 100
  • 205 a.a.
蛋白主名 其他名称

CD83 antigen

B-cell activation protein

CD83 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CD83 Q01151 FATE1 Homo sapiens Q969F0
Validated Y2H
32296183
种属内
CD83 Q01151 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
种属内
CD83 Q01151 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD83 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72703 CD83 Protein, Human (HEK293, Fc) Q01151 (T20-A143) ≥95%
HY-P75377 CD83 Protein, Human (HEK293, His) Q01151 (T20-A143) ≥95%

关联疾病

疾病名称 别名
Plague

Yersiniosis

Yersinia Infections

Infection By Yersinia Pestis

Pasteurella Pestis Infection

Pestilential Fever

Yersinia Pestis Infection
Sulfamethoxazole Allergy

Smx Allergy

Smz Allergy

Sulphamethoxazole Allergy
Herpes Zoster

Shingles

Zoster

Herpes Zona

Herpes Zoster Disease

Zona Zoster

Herpes Zoster Of Skin And Mucous Membranes

Zoster Nos

Zoster With Nervous System Involvement
Rift Valley Fever

Rfv - [Rift Valley Fever]
Anal Gland Neoplasm

Anal Gland Neoplasms
Temporal Arteritis

Polymyalgia Rheumatica

Giant Cell Arteritis

Cranial Arteritis

Horton Disease

Gca

Horton'S Disease

Rhizomelic Pseudopolyarthritis

Arteritis Cranialis

Arteritis Temporalis

Horton'S Arteritis

Horton'S Giant Cell Arteritis

Horton'S Temporal Arteritis

Horton'S Syndrome

Gca - [Giant Cell Arteritis]

Senile Arthritis

Polymyalgia Arteritica

Pmr - [Polymyalgia Rheumatica]

Forestier-Certonciny Syndrome

Rheumatic Polymyalgia

Polymyalgia
Common Variable Immunodeficiency

Cvid

Common Variable Agammaglobulinemia

Common Variable Immune Deficiency

Acquired Hypogammaglobulinemia

Hypogamma-Globulinemia, Acquired

Idiopathic Immunoglobulin Deficiency

Primary Antibody Deficiency

Primary Hypogammaglobulinemia

Acquired Agammaglobulinemia

Sporadic Hypogammaglobulinemia

Common Variable Hypogamma-Globulinemia

Immunoglobulin Deficiency, Late-Onset

Common Variable Hypogammaglobulinemia

Immunodeficiency, Common Variable
Cardiomyopathy, Dilated, 1c, With Or Without Left Ventricular Noncompaction

Left Ventricular Noncompaction 3

Dilated Cardiomyopathy 1c

CMD1C

Cardiomyopathy, Hypertrophic, 24

Dilated Cardiomyopathy With Left Ventricular Noncompaction

Cardiomyopathy, Dilated, 1c, With Or Without Lvnc

Cmdc1

Dilated Cardiomyopathy 1c With Or Without Left Ventricular Noncompaction

Cardiomyopathy, Dilated 1c, With Or Without Left Ventricular Non-Compaction

Cardiomyopathy Dilated With Left Ventricular Noncompaction

Cardiomyopathy, Familial Hypertrophic 24

CMH24

Left Ventricular Non-Compaction 3

LVNC3

Cardiomyopathy, Dilated 1c

Familial Hypertrophic Cardiomyopathy 24

Cardiomyopathy, Dilated, 1c
Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02272 CD83 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CD83 VGNC VGNC:38977
Mus musculus CD83 MGD MGI:1328316
Felis catus CD83 VGNC VGNC:60641
Rattus norvegicus CD83 RGD RGD:1309677
Bos taurus CD83 VGNC VGNC:27050
Macaca mulatta CD83 VGNC VGNC:70783
Macaca fascicularis CD83 NCBI NCBI:102133406
Others CD83 NCBI
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