TCEAL1 - transcription elongation factor A like 1 Gene

中文名称：转录延伸因子 A 样 1

种属: Homo sapiens

同用名: p21; SIIR; WEX9; pp21

关于 TCEAL1

功能概要

该基因编码转录延伸因子 A (SII) 样 (TCEAL) 基因家族的成员。该家族的成员可能作为核磷蛋白发挥作用，以启动子上下文相关的方式调节转录。编码的蛋白质类似于转录延伸因子 A/转录因子 SII，包含锌指状基序以及与转录因子 SII Pol II 结合区相关的序列。它可能通过与其他转录调节因子的蛋白质-蛋白质相互作用而不是通过直接结合 DNA 来发挥作用。多个家族成员位于 X 染色体上。可变剪接导致编码单个亚型的多个转录变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]