2. Gene
  3. Rnf111 - ring finger 111 Gene

Rnf111 - ring finger 111 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ARK; Arkadia

基因 ID: 93836 | 基因类型: protein coding

关于 Rnf111

功能概要

Enables ubiquitin protein Ligase activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cellular protein metabolic process; positive regulation of protein ubiquitination; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Part of protein-containing complex. Is expressed in several structures, including heart; nervous system; testis; and urinary system. Orthologous to human RNF111 (ring finger protein 111). [provided by Alliance of Genome Resources, Apr 2022]

Rnf111 基因产物(3)

mRNA Protein Name
NM_001357494.1 NP_001344423.1 E3 ubiquitin-protein ligase Arkadia isoform 2
NM_001374753.1 NP_001361682.1 E3 ubiquitin-protein ligase Arkadia isoform 3
NM_033604.3 NP_291082.1 E3 ubiquitin-protein ligase Arkadia isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16601693 MGI
enables ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
16601693 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
11298452 MGI
acts upstream of or within positive regulation of protein ubiquitination IDA
IDA: 通过直接分析推断
16601693 MGI
acts upstream of or within positive regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
16601693 MGI
acts upstream of or within positive regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
16601693 MGI
acts upstream of or within positive regulation of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
16601693 MGI
involved in positive regulation of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
16601693 MGI
acts upstream of or within protein polyubiquitination IDA
IDA: 通过直接分析推断
16601693 MGI
acts upstream of or within protein polyubiquitination IGI
IGI: 通过遗传相互作用推断
16601693 MGI
acts upstream of or within protein polyubiquitination IMP
IMP: 通过突变表型推断
16601693 MGI
involved in protein polyubiquitination IMP
IMP: 通过突变表型推断
16601693 MGI
acts upstream of or within ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
16601693 MGI
acts upstream of or within ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
16601693 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16601693 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11555636 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
16601693 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase Arkadia

RING finger protein 111

RING-type E3 ubiquitin transferase Arkadia

Rnf111 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Rnf111 Q99ML9 Axin1 Mus musculus O35625
Anti Tag CoIP
16601693
种属内
Rnf111 Q99ML9 Axin1 Mus musculus O35625
Pull Down
16601693
种属间
Rnf111 Q99ML9 SMAD7 Homo sapiens O15105
Anti Tag CoIP
16601693
种属间
Rnf111 Q99ML9 AXIN1 Homo sapiens O15169
Imaging
16601693
种属间
Rnf111 Q99ML9 AXIN1 Homo sapiens O15169
Anti Tag CoIP
16601693
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12036 RNF111 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rnf111 NCBI NCBI:54778
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