2. Gene
  3. SLC22A14 - solute carrier family 22 member 14 Gene

SLC22A14 - solute carrier family 22 member 14 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 22 成员 14

种属: Homo sapiens

同用名: OCTL2; OCTL4; ORCTL4

基因 ID: 9389 | 基因类型: protein coding

关于 SLC22A14

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:38,278,832-38,318,575 (from NCBI)

This gene has 4 transcripts (splice variants), 482 orthologues and 22 paralogues. Restricted expression toward testis (RPKM 3.4).

功能概要

该基因编码有机阳离子转运蛋白家族的一个成员。它位于与该家族的另一个成员有机阳离子转运蛋白如 3 的基因簇中。编码的蛋白质是一种跨膜蛋白，被认为可以转运小分子，并且由于这种蛋白质在几个物种中是保守的，因此建议具有在哺乳动物系统中的基础性作用。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 3. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

SLC22A14 基因产物(2)

mRNA Protein Name
NM_001320033.2 NP_001306962.1 solute carrier family 22 member 14
NM_004803.4 NP_004794.2 solute carrier family 22 member 14
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables riboflavin transmembrane transporter activity IDA
IDA: 通过直接分析推断
33882315 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
33882315 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC22A14 蛋白结构

Sugar_tr

Sugar_tr: Sugar (and other) transporter (189 - 569)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 594 a.a.
蛋白主名 其他名称

solute carrier family 22 member 14

organic cation transporter-like 4

SLC22A14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC22A14 Q9Y267 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra SLC22A14 Q9Y267 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13067 SLC22A14 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLC22A14 MGD MGI:2685974
Felis catus SLC22A14 VGNC VGNC:68654
Canis familiaris SLC22A14 VGNC VGNC:46275
Rattus norvegicus SLC22A14 RGD RGD:1306470
Bos taurus SLC22A14 VGNC VGNC:34722
Macaca mulatta SLC22A14 VGNC VGNC:77594
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