2. Gene
  3. SFXN5 - sideroflexin 5 Gene

SFXN5 - sideroflexin 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：sideroflexin 5

种属: Homo sapiens

同用名: BBG-TCC; SLC56A5

基因 ID: 94097 | 基因类型: protein coding

关于 SFXN5

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:72,942,036-73,071,712 (from NCBI)

This gene has 22 transcripts (splice variants), 252 orthologues and 4 paralogues. Broad expression in brain (RPKM 13.0), liver (RPKM 3.8) and 20 other tissues.

功能概要

预测可启用柠檬酸盐跨膜转运蛋白活性。预计参与柠檬酸盐转运和线粒体跨膜转运。位于线粒体中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable citrate transmembrane transporter activity. Predicted to be involved in citrate transport and mitochondrial transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SFXN5 基因产物(20)

mRNA Protein Name
NM_001330400.2 NP_001317329.1 sideroflexin-5 isoform 1
NM_001330401.2 NP_001317330.1 sideroflexin-5 isoform 3
NM_001330402.2 NP_001317331.1 sideroflexin-5 isoform 4
NM_001330403.2 NP_001317332.1 sideroflexin-5 isoform 5 precursor
NM_001330404.2 NP_001317333.1 sideroflexin-5 isoform 6
NM_001330405.2 NP_001317334.1 sideroflexin-5 isoform 7 precursor
NM_001330406.2 NP_001317335.1 sideroflexin-5 isoform 8 precursor
NM_001330407.2 NP_001317336.1 sideroflexin-5 isoform 9
NM_001330408.2 NP_001317337.1 sideroflexin-5 isoform 10
NM_001330410.2 NP_001317339.1 sideroflexin-5 isoform 6
NM_001330411.2 NP_001317340.1 sideroflexin-5 isoform 11
NM_001330412.2 NP_001317341.1 sideroflexin-5 isoform 11
NM_001371737.1 NP_001358666.1 sideroflexin-5 isoform 12
NM_001371738.1 NP_001358667.1 sideroflexin-5 isoform 13
NM_001371739.1 NP_001358668.1 sideroflexin-5 isoform 14
NM_001371740.1 NP_001358669.1 sideroflexin-5 isoform 15
NM_001371741.1 NP_001358670.1 sideroflexin-5 isoform 16
NM_001371742.1 NP_001358671.1 sideroflexin-5 isoform 17
NM_001371743.1 NP_001358672.1 sideroflexin-5 isoform 18
NM_144579.3 NP_653180.1 sideroflexin-5 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
30442778 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SFXN5 蛋白结构

Mtc

Mtc: Tricarboxylate carrier (32 - 340)

  • 0
  • 100
  • 200
  • 300
  • 340 a.a.
蛋白主名 其他名称

sideroflexin-5

SFXN5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SFXN5 Q8TD22 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra SFXN5 Q8TD22 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra SFXN5 Q8TD22 TMPPE Homo sapiens Q6ZT21
Y2H Array
32296183
Intra SFXN5 Q8TD22 TMPPE Homo sapiens Q6ZT21
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 STOM Homo sapiens P27105
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 STOM Homo sapiens P27105
Y2H Array
32296183
Intra SFXN5 Q8TD22 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra SFXN5 Q8TD22 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
Intra SFXN5 Q8TD22 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra SFXN5 Q8TD22 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 APOL2 Homo sapiens Q9BQE5
Y2H Array
32296183
Intra SFXN5 Q8TD22 APOL2 Homo sapiens Q9BQE5
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra SFXN5 Q8TD22 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra SFXN5 Q8TD22 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra SFXN5 Q8TD22 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra SFXN5 Q8TD22 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra SFXN5 Q8TD22 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra SFXN5 Q8TD22 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency 18

Growth And Developmental Delay-Hypotonia-Vision Impairment-Lactic Acidosis Syndrome

COXPD18

Combined Oxidative Phosphorylation Deficiency, Type 18
Parkinson Disease 21

PARK21

Parkinson'S Disease 21

Parkinson Disease, Type 21
Sengers Syndrome

Mitochondrial Dna Depletion Syndrome 10

Cardiomyopathy And Cataract

Cataract And Cardiomyopathy

MTDPS10

Congenital Cataract-Hypertrophic Cardiomyopathy-Mitochondrial Myopathy Syndrome

Cardiomyopathic Mitochondrial Dna Depletion Syndrome 10

Senger Syndrome
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12789 SFXN5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SFXN5 VGNC VGNC:65073
Macaca mulatta SFXN5 VGNC VGNC:77243
Bos taurus SFXN5 VGNC VGNC:34534
Mus musculus SFXN5 MGD MGI:2137681
Rattus norvegicus SFXN5 RGD RGD:628706
Canis familiaris SFXN5 VGNC VGNC:46090
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