1. Gene
  2. Tnfrsf21 - tumor necrosis factor receptor superfamily, member 21 Gene

Tnfrsf21 - tumor necrosis factor receptor superfamily, member 21 Gene

种属: Mus musculus

同用名: DR6; TR7

基因 ID: 94185 | 基因类型: protein coding

关于 Tnfrsf21

功能概要

Involved in several processes, including negative regulation of cytokine production; negative regulation of lymphocyte proliferation; and oligodendrocyte apoptotic process. Located in axon. Is intrinsic component of plasma membrane. Is expressed in several structures, including alimentary system; lung; metanephros; nervous system; and nose. Orthologous to human TNFRSF21 (TNF Receptor Superfamily member 21). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf21 基因产物(1)

mRNA Protein Name
NM_178589.3 NP_848704.1 tumor necrosis factor receptor superfamily member 21 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell apoptotic process IMP
IMP: 通过突变表型推断
12515813 MGI
involved in T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
11485735 MGI
involved in adaptive immune response IMP
IMP: 通过突变表型推断
11485735 MGI
involved in humoral immune response IMP
IMP: 通过突变表型推断
11485735 MGI
involved in myelination IMP
IMP: 通过突变表型推断
21725297 MGI
involved in negative regulation of B cell proliferation IMP
IMP: 通过突变表型推断
12515813 MGI
involved in negative regulation of T cell proliferation IMP
IMP: 通过突变表型推断
11485735 MGI
involved in negative regulation of interleukin-10 production IMP
IMP: 通过突变表型推断
11485735 MGI
involved in negative regulation of interleukin-13 production IMP
IMP: 通过突变表型推断
11485735 MGI
involved in negative regulation of interleukin-5 production IMP
IMP: 通过突变表型推断
11485735 MGI
involved in neuron apoptotic process IMP
IMP: 通过突变表型推断
23559013 MGI
involved in oligodendrocyte apoptotic process IMP
IMP: 通过突变表型推断
21725297 MGI
involved in regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
21725297 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
12515813 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 21

Death receptor 6

TNFR-related death receptor-6

重组 Tnfrsf21 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72664 DR6/TNFRSF21 Protein, Mouse (HEK293, Fc-His) Q9EPU5 (Q42-H349) ≥95%
HY-P75278 DR6/TNFRSF21 Protein, Mouse (HEK293, His) Q9EPU5 (Q42-H349) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfrsf21 NCBI NCBI:27242
Macaca fascicularis Tnfrsf21 NCBI NCBI:101925746
Rattus norvegicus Tnfrsf21 NCBI NCBI:316256