CDYL - chromodomain Y like Gene

中文名称：染色体 Y 样

种属: Homo sapiens

同用名: CDYL1

关于 CDYL

功能概要

染色体 Y 是灵长类动物特异性 Y 染色体基因家族，仅在睾丸中表达并与不育有关。虽然 Y 连锁基因是睾丸特异性的，但这种常染色体基因普遍表达。 Y 连锁基因是通过对该基因的 mRNA 进行逆转录转座，然后扩增逆转录基因而产生的。由该基因超家族编码的蛋白质具有一个染色质结构域，一个与染色质结合和基因抑制有关的基序，以及一个被认为与组蛋白乙酰化有关的催化结构域。多种蛋白质由该基因的转录变体编码。[RefSeq 提供，2008 年 7 月]

Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]