ULK2 - unc-51 like autophagy activating kinase 2 Gene

中文名称：unc-51 样自噬激活激酶 2

种属: Homo sapiens

同用名: ATG1B; Unc51.2

关于 ULK2

功能概要

该基因编码的蛋白质类似于秀丽隐杆线虫中参与轴突伸长的丝氨酸/苏氨酸激酶。这种蛋白质的结构类似于秀丽隐杆线虫蛋白质，因为这两种蛋白质都有一个 N 末端激酶结构域、一个中央富含脯氨酸/丝氨酸 (PS) 结构域和一个 C 末端 (C) 结构域。该基因位于 17 号染色体上的 Smith-Magenis 综合征区域内。已鉴定出编码相同蛋白质的可变剪接转录物变体。[RefSeq 提供，2008 年 12 月]

This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]