2. Gene
  3. CD72 - CD72 molecule Gene

CD72 - CD72 molecule Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CD72 分子

种属: Homo sapiens

同用名: LYB2; CD72b

基因 ID: 971 | 基因类型: protein coding

关于 CD72

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:35,609,982-35,646,857 (from NCBI)

This gene has 10 transcripts (splice variants) and 126 orthologues. Biased expression in lymph node (RPKM 32.2), spleen (RPKM 30.4) and 4 other tissues.

功能概要

预测启用信号受体结合活性。预计参与细胞粘附。是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable signaling receptor binding activity. Predicted to be involved in cell adhesion. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CD72 基因产物(1)

mRNA Protein Name
NM_001782.3 NP_001773.1 B-cell differentiation antigen CD72
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
1711157 GOA
enables transmembrane signaling receptor activity IDA
IDA: 通过直接分析推断
27810925 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of B cell receptor signaling pathway IDA
IDA: 通过直接分析推断
1711157 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
1711157 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CD72 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (251 - 352)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
蛋白主名 其他名称

B-cell differentiation antigen CD72

CD72 antigen

CD72 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CD72 P21854 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
种属内
CD72 P21854 LSMEM2 Homo sapiens Q8N112
Validated Y2H
32296183
种属内
CD72 P21854 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
种属内
CD72 P21854 LRRC25 Homo sapiens Q8N386
Y2H Array
32296183
种属内
CD72 P21854 LRRC25 Homo sapiens Q8N386
Validated Y2H
32296183
种属内
CD72 P21854 LRRC25 Homo sapiens Q8N386
Y2H Prey Pooling
32296183
种属内
CD72 P21854 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
种属内
CD72 P21854 MS4A3 Homo sapiens Q96HJ5
Validated Y2H
32296183
种属内
CD72 P21854 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
种属内
CD72 P21854 NRG1 Homo sapiens Q02297-10
Y2H Prey Pooling
32296183
种属内
CD72 P21854 NRG1 Homo sapiens Q02297-10
Validated Y2H
32296183
种属内
CD72 P21854 NRG1 Homo sapiens Q02297-10
Y2H Array
32296183
种属内
CD72 P21854 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
CD72 P21854 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
种属内
CD72 P21854 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
种属内
CD72 P21854 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
种属内
CD72 P21854 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
种属内
CD72 P21854 CGRRF1 Homo sapiens Q99675
Y2H Array
32296183
种属内
CD72 P21854 CGRRF1 Homo sapiens Q99675
Y2H Prey Pooling
32296183
种属内
CD72 P21854 CGRRF1 Homo sapiens Q99675
Validated Y2H
32296183
种属内
CD72 P21854 ATP6AP2 Homo sapiens O75787
Y2H Prey Pooling
32296183
种属内
CD72 P21854 ATP6AP2 Homo sapiens O75787
Y2H Array
32296183
种属内
CD72 P21854 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
种属内
CD72 P21854 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
种属内
CD72 P21854 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
种属内
CD72 P21854 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
种属内
CD72 P21854 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
种属内
CD72 P21854 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
种属内
CD72 P21854 BIK Homo sapiens Q13323
Y2H Array
32296183
种属内
CD72 P21854 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
种属内
CD72 P21854 BIK Homo sapiens Q13323
Validated Y2H
32296183
种属内
CD72 P21854 GRAMD1C Homo sapiens Q8IYS0
Validated Y2H
32296183
种属内
CD72 P21854 GRAMD1C Homo sapiens Q8IYS0
Y2H Array
32296183
种属内
CD72 P21854 GRAMD1C Homo sapiens Q8IYS0
Y2H Prey Pooling
32296183
种属内
CD72 P21854 MS4A7 Homo sapiens Q9GZW8
Y2H Prey Pooling
32296183
种属内
CD72 P21854 MS4A7 Homo sapiens Q9GZW8
Validated Y2H
32296183
种属内
CD72 P21854 MS4A7 Homo sapiens Q9GZW8
Y2H Array
32296183
种属内
CD72 P21854 CLDN7 Homo sapiens O95471
Y2H Array
32296183
种属内
CD72 P21854 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD72 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72711 CD72 Protein, Human (Trx, His) P21854 (R117-C226) ≥95%

关联疾病

疾病名称 别名
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02265 CD72 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CD72 VGNC VGNC:38971
Bos taurus CD72 VGNC VGNC:27045
Macaca mulatta CD72 VGNC VGNC:70778
Rattus norvegicus CD72 RGD RGD:1309757
Mus musculus CD72 MGD MGI:88345
Felis catus CD72 VGNC VGNC:60637
Others CD72 NCBI
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