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  2. RASSF2 - Ras association domain family member 2 Gene

RASSF2 - Ras association domain family member 2 Gene

中文名称:Ras 关联域家族成员 2

种属: Homo sapiens

同用名: CENP-34; RASFADIN

基因 ID: 9770 | 基因类型: protein coding

关于 RASSF2

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:4,780,023-4,823,608 (from NCBI)

This gene has 3 transcripts (splice variants), 215 orthologues and 5 paralogues. Broad expression in brain (RPKM 57.7), bone marrow (RPKM 38.0) and 16 other tissues.

功能概要

该基因编码一种包含 Ras 关联结构域的蛋白质。与牛羊相似,该基因位于朊病毒基因附近。已经报道了编码相同亚型的两个可变剪接的转录物。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008]

RASSF2 基因产物(2)

mRNA Protein Name
NM_014737.3 NP_055552.1 ras association domain-containing protein 2
NM_170774.2 NP_739580.1 ras association domain-containing protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12732644 GOA
enables protein kinase activity IGI
IGI: 通过遗传相互作用推断
19962960 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19525978 GOA
located in kinetochore IDA
IDA: 通过直接分析推断
20813266 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19525978 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
19962960 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RASSF2 蛋白结构

RA

RA: Ras association (RalGDS/AF-6) domain (180 - 264)

  • 0
  • 100
  • 200
  • 300
  • 326 a.a.
蛋白主名 其他名称

ras association domain-containing protein 2

Ras association (RalGDS/AF-6) domain family 2

RASSF2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RASSF2 P50749 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra RASSF2 P50749 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra RASSF2 P50749 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra RASSF2 P50749 NEK7 Homo sapiens Q8TDX7
Y2H Array
32814053
Intra RASSF2 P50749 NEK7 Homo sapiens Q8TDX7
Y2H Pooling
32814053
Intra RASSF2 P50749 NEK7 Homo sapiens Q8TDX7
Validated Y2H
32814053
Intra RASSF2 P50749 S100Z Homo sapiens Q8WXG8
Y2H Prey Pooling
32296183
Intra RASSF2 P50749 S100Z Homo sapiens Q8WXG8
Y2H Array
32296183
Intra RASSF2 P50749 S100Z Homo sapiens Q8WXG8
Validated Y2H
32296183
Intra RASSF2 P50749 SUV39H1 Homo sapiens O43463
Y2H
23455924
Intra RASSF2 P50749 SUV39H1 Homo sapiens O43463
Anti Tag CoIP
23455924
Intra RASSF2 P50749 STK4 Homo sapiens Q13043
Anti Tag CoIP
24366813
Intra RASSF2 P50749 STK4 Homo sapiens Q13043
Anti Tag CoIP
33961781
Intra RASSF2 P50749 STK4 Homo sapiens Q13043
Anti Tag CoIP
24255178
Intra RASSF2 P50749 STK4 Homo sapiens Q13043
BioID
24255178
Intra RASSF2 P50749 KDM1A Homo sapiens O60341
Anti Tag CoIP
23455924
Intra RASSF2 P50749 KDM1A Homo sapiens O60341
Y2H
23455924
Intra RASSF2 P50749 GFAP Homo sapiens P14136
Y2H Pooling
32814053
Intra RASSF2 P50749 GFAP Homo sapiens P14136
Validated Y2H
32814053
Intra RASSF2 P50749 GFAP Homo sapiens P14136
Y2H Array
32814053
Intra RASSF2 P50749 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra RASSF2 P50749 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
Intra RASSF2 P50749 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
BioID
24255178
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
Anti Tag CoIP
24255178
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
Anti Tag CoIP
33961781
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
Anti Tag CoIP
24366813
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
Anti Tag CoIP
28514442
Intra RASSF2 P50749 STK3 Homo sapiens Q13188
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RASSF2 VGNC VGNC:45380
Macaca mulatta RASSF2 VGNC VGNC:76674
Mus musculus RASSF2 MGD MGI:2442060
Felis catus RASSF2 VGNC VGNC:69253
Rattus norvegicus RASSF2 RGD RGD:1305551
Bos taurus RASSF2 VGNC VGNC:33758