2. Gene
  3. UBAP2L - ubiquitin associated protein 2 like Gene

UBAP2L - ubiquitin associated protein 2 like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：泛素相关蛋白 2 样

种属: Homo sapiens

同用名: NICE4; NICE-4

基因 ID: 9898 | 基因类型: protein coding

关于 UBAP2L

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:154,220,172-154,271,510 (from NCBI)

This gene has 20 transcripts (splice variants), 212 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 26.7), placenta (RPKM 21.3) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与精子与透明带的结合活性和应激颗粒组装。作用于造血干细胞稳态的上游或内部。 PcG 蛋白复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in binding activity of sperm to zona pellucida and stress granule assembly. Acts upstream of or within hematopoietic stem cell homeostasis. Part of PcG protein complex. [provided by Alliance of Genome Resources, Apr 2022]

UBAP2L 基因产物(24)

mRNA Protein Name
NM_001127320.3 NP_001120792.1 ubiquitin-associated protein 2-like isoform b
NM_001287815.1 NP_001274744.1 ubiquitin-associated protein 2-like isoform c
NM_001287816.1 NP_001274745.1 ubiquitin-associated protein 2-like isoform d
NM_001330730.1 NP_001317659.1 ubiquitin-associated protein 2-like isoform e
NM_001375612.1 NP_001362541.1 ubiquitin-associated protein 2-like isoform f
NM_001375614.1 NP_001362543.1 ubiquitin-associated protein 2-like isoform g
NM_001375615.1 NP_001362544.1 ubiquitin-associated protein 2-like isoform h
NM_001375616.1 NP_001362545.1 ubiquitin-associated protein 2-like isoform h
NM_001375617.1 NP_001362546.1 ubiquitin-associated protein 2-like isoform i
NM_001375618.1 NP_001362547.1 ubiquitin-associated protein 2-like isoform a
NM_001375619.1 NP_001362548.1 ubiquitin-associated protein 2-like isoform a
NM_001375620.1 NP_001362549.1 ubiquitin-associated protein 2-like isoform j
NM_001375621.1 NP_001362550.1 ubiquitin-associated protein 2-like isoform j
NM_001375622.1 NP_001362551.1 ubiquitin-associated protein 2-like isoform j
NM_001375623.1 NP_001362552.1 ubiquitin-associated protein 2-like isoform k
NM_001375624.1 NP_001362553.1 ubiquitin-associated protein 2-like isoform l
NM_001375625.1 NP_001362554.1 ubiquitin-associated protein 2-like isoform e
NM_001375626.1 NP_001362555.1 ubiquitin-associated protein 2-like isoform m
NM_001375627.1 NP_001362556.1 ubiquitin-associated protein 2-like isoform m
NM_001375628.1 NP_001362557.1 ubiquitin-associated protein 2-like isoform n
NM_001375629.1 NP_001362558.1 ubiquitin-associated protein 2-like isoform b
NM_001375630.1 NP_001362559.1 ubiquitin-associated protein 2-like isoform b
NM_001375631.1 NP_001362560.1 ubiquitin-associated protein 2-like isoform b
NM_014847.4 NP_055662.3 ubiquitin-associated protein 2-like isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19945174 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in binding of sperm to zona pellucida IMP
IMP: 通过突变表型推断
19945174 GOA
acts upstream of or within hematopoietic stem cell homeostasis IGI
IGI: 通过遗传相互作用推断
25185265 GOA
involved in positive regulation of stress granule assembly IDA
IDA: 通过直接分析推断
32302570 GOA
involved in stress granule assembly IMP
IMP: 通过突变表型推断
29395067 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of PcG protein complex IDA
IDA: 通过直接分析推断
25185265 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

UBAP2L 蛋白结构

DUF3697

DUF3697: Ubiquitin-associated protein 2 (495 - 526)

  • 0
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  • 1087 a.a.
蛋白主名 其他名称

ubiquitin-associated protein 2-like

protein NICE-4

UBAP2L 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
UBAP2L Q14157 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
种属内
UBAP2L Q14157 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
种属间
UBAP2L Q14157 P0DTD1-PRO_0000449629 SARS-CoV-2 P0DTD1-PRO_0000449629
Y2H Array
36217030
种属内
UBAP2L Q14157 FXR2 Homo sapiens P51116
Y2H Prey Pooling
32296183
种属内
UBAP2L Q14157 FXR2 Homo sapiens P51116
Y2H Array
32296183
种属内
UBAP2L Q14157 FXR2 Homo sapiens P51116
TAP
24981860
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spinal Cord Neuroblastoma

Neuroblastoma Of The Spinal Cord
Spinal Cord Primitive Neuroectodermal Neoplasm

Spinal Cord Pnet

Spinal Cord Primitive Neuroectodermal Tumor
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15330 UBAP2L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus UBAP2L VGNC VGNC:36573
Mus musculus UBAP2L MGD MGI:1921633
Rattus norvegicus UBAP2L RGD RGD:1308707
Macaca mulatta UBAP2L VGNC VGNC:79825
Canis familiaris UBAP2L VGNC VGNC:48047
Felis catus UBAP2L VGNC VGNC:66754
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